Copyright
©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 14, 2014; 20(10): 2613-2623
Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2613
Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2613
Non-invasive prediction of forthcoming cirrhosis-related complications
Wonseok Kang, Seung Up Kim, Sang Hoon Ahn, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul 120-752, South Korea
Wonseok Kang, Seung Up Kim, Sang Hoon Ahn, Liver Cirrhosis Clinical Research Center, Seoul 120-752, South Korea
Author contributions: Kang W and Kim SU contributed equally to this work; Kang W and Kim SU contributed to the concept and design of the study, literature search, analysis and interpretation of data and drafting of the manuscript; Ahn SH contributed to the concept and design of the study, drafting of the manuscript, obtained funding and supervised the study.
Supported by The Liver Cirrhosis Clinical Research Center, a grant from the Korea Healthcare Technology RandD Project, Ministry of Health and Welfare, South Korea, No. HI10C2020; the Bilateral International Collaborative RandD Program from the Ministry of Knowledge Economy, South Korea
Correspondence to: Sang Hoon Ahn, MD, PhD, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. ahnsh@yuhs.ac
Telephone: +82-2-22281936 Fax: +82-2-3936884
Received: November 8, 2013
Revised: January 4, 2014
Accepted: February 17, 2014
Published online: March 14, 2014
Revised: January 4, 2014
Accepted: February 17, 2014
Published online: March 14, 2014
Core Tip
Core tip: In this article, we summarized recent longitudinal studies of non-invasive methods - including transient elastography, European Liver Fibrosis scoring system, Fibrotest, and acoustic radiation force impulse technique - for predicting forthcoming complications related to liver cirrhosis. We also discussed the clinical value of currently available non-invasive methods based on evidence from the literature and finally proposed areas for future research directions.