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©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 209-209
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.209
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.209
Cisapride in treatment of chronic functional constipation in 23 patients
Chang-Hua Wang, Ai-Xiu Ding, Xing-Jin Lu, Changzhou Guanghua Hospital, Changzhou 213001, Jiangsu Province, China
Author contributions: All authors contributed equally to the work.
Received: December 11, 1995
Revised: January 21, 1996
Accepted: July 19, 1996
Published online: September 15, 1996
Revised: January 21, 1996
Accepted: July 19, 1996
Published online: September 15, 1996
Abstract
AIM: The purpose of the study is to observe the efficacy and safety of cisapride in treatment of chronic functional constipation.
METHODS: 23 patients (male 14, female 9, age 58 ± 7 years) of chronic functional constipation were treated with cisapride in a dose of 10 mg tid po for 4 wk.
RESULTS: Interval time of defecation and time for defecation became shorter than those of before treatment (P < 0.01). The pronounced response rate and the total response rate were 52.2% and 82.6%, respectively. The side effects were mild.
CONCLUSION: Cisapride was safe and effective in treatment of chronic functional constipation.
Keywords: Cisapride, Constipation