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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jan 21, 2008; 14(3): 408-412
Published online Jan 21, 2008. doi: 10.3748/wjg.14.408
Published online Jan 21, 2008. doi: 10.3748/wjg.14.408
Recent trends in the surgical management of inflammatory bowel disease
Robert E Roses, John L Rombeau, University of Pennsylvania School of Medicine Philadelphia, Pennsylvania; Temple University School of Medicine, Philadelphia, Pennsylvania, United States
Correspondence to: John Rombeau, MD, Temple University Hospital 4th Fl, Zone C, 3401 N. Broad St, Philadelphia, PA 19140, United States. john.rombeau@tuhs.temple.edu
Telephone: +1-215-7077725
Fax: +1-215-7073945
Received: May 18, 2007
Revised: July 4, 2007
Published online: January 21, 2008
Revised: July 4, 2007
Published online: January 21, 2008
Abstract
Surgery is required in the vast majority of patients with Crohn’s disease (CD) and in approximately one-third of patients with ulcerative colitis (UC). Similar to medical treatments for IBD, significant advances have occurred in surgery. Advances in CD include an emphasis upon conservatism as exemplified by more limited resections, strictureplasties, and laparoscopic resections. The use of probiotics in selected patients has improved the outcome in patients with pouchitis following restorative proctocolectomy for UC. It is anticipated that ongoing discoveries in the molecular basis of IBD will in turn identify those patients who will best respond to surgery.