In 2019, the World Journal of Hepatology (WJH) has published the 5^th issue which containing 7 articles including 1 opinion review, 1 review, 1 original article, 1 systematic review, 1 meta-analysis, and 2 case reports contributed by scientists worldwide. Among these comprehensive articles are (1) “Hepatitis C virus cure with direct acting antivirals: Clinical, economic, societal and patient value for China”, a review by Shan-Lian Hu, Professor, et al from School of Public Health, Fudan University, China; (2) “Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus coinfection in human immunodeficiency virus infected individuals”, a basic study by Ke-Qin Hu, FAASLD, et al University of California, United States; and (3) “Successful treatment of noncirrhotic portal hypertension with eculizumab in paroxysmal nocturnal hemoglobinuria: A case report”, a case report by Alexandra Alexopoulou, MD, PhD, Associate Professor, et al National and Kapodistrian University of Athens, Hippokration General Hospital, Greece, etc. We invite you to peruse all 7 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 11, Issue 5, May 27, 2019.

Figure 1 The cover of the issue. Associate Editor of World Journal of Hepatology, Yeong Yeh Lee, FACG, FACP, FRCP (C), MD, PhD, Doctor, Professor, Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kota Bahru 16150, Kelantan, Malaysia.

We encourage hepatologists worldwide to submit manuscripts to the WJH describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.