In 2018, the World Journal of Gastroenterology (WJG) has published the 27^th issue which containing 11 articles including 6 reviews, and 5 original articles, contributed by scientists worldwide. Among these comprehensive articles are (1) “MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside”, a review by Kenneth KW To, PhD, Associate Professor, et al fromSchool of Pharmacy, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong, China; (2) “Liver intravoxel incoherent motion diffusion-weighted imaging for the assessment of hepatic steatosis and fibrosis in children”, a retrospective study by Mi-Jung Lee, MD, PhD, Assistant Professor, et al from Department of Radiology, Severance Hospital, Severance Pediatric Liver Disease Research Group, Research Institute of Radiological Science, Yonsei University College of Medicine, South Korea; and (3) “New fecal test for non-invasive Helicobacter pylori detection: A diagnostic accuracy study”, a clinical trials study by Enzo Ierardi, MD, Associate Professor, et al from Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Italy, etc. We invite you to peruse all 11 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 24, Issue 27, July 21, 2018.

Figure 1 The cover of the issue. Editorial board member of World Journal of Gastroenterology, C. Mel Wilcox, MD, Doctor, Professor, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 35294, United States

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue.