In 2016, the World Journal of Hepatology (WJH) has published the 30^th issue which containing 5 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Insights for hepatitis C virus related hepatocellular carcinoma genetic biomarkers: Early diagnosis and therapeutic intervention”, a Review by Wafaa M Ezzat, MD, Professor, et al from Department of Internal Medicine, National Research Center, Egypt; (2) “Retrospective study of the associations between hepatitis C virus infection and metabolic factors”, an Original Article by Elchanan Nussinson, MD, et al from Gastroenterology Institute, Emek Medical Center, Israel, etc. We invite you to peruse all 5 articles in this issue, as they present the latest research progress/findings and provide insightful comments in hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 8, Issue 30, October 28, 2016.

Figure 1 The cover of the issue. Editorial Board Member of World Journal of Hepatology, Nikolaos G Symeonidis, MD, MSc, PhD, Surgeon, Second Propedeutical Department of Surgery, Aristotle University of Thessaloniki, Medical School, Hippokratio General Hospital, 54642 Thessaloniki, Greece

The WJH is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of hepatology. It was launched on October 31, 2009 and is published three issues per month (36 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage hepatologists worldwide to submit manuscripts to the WJH describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at: http://www.wjgnet.com/1948-5182/e-journal.htm.