Mortality of critical care interventions in the COVID-19: A systematic review

Table 1 Studies included in a systematic review of mortality and critical care interventions in coronavirus disease 2019

Ref.	Data available					Newcastle-Ottawa quality scale
	Intensive care	Mechanical ventilation	Hemodialysis	ECMO	CPR
Bhatraju et al[6]	X	X				4
Shao et al[18]					X	6
Arentz et al[22]	X					4
Cai et al[23]	X	X				6
Cao et al[24]	X	X	X			6
Chen et al[25]	X					5
Grasselli et al[26]	X					5
Han et al[27]	X					7
Huang et al[28]	X					7
Intensive Care National Audit and Research Centre[29]	X	X	X			5
Li et al[30]	X	X		X		4
Ling et al[31]	X	X				6
Wang et al[32]	X	X				7
Wang et al[33]	X		X			7
Wang et al[34]	X	X				6
Wu et al[35]	X	X				6
Yang et al[36]	X	X	X	X		7
Zhou et al[37]	X	X	X			7
Deng et al[38]		X				6
Grein et al[39]		X				5

ECMO: Extracoropreal membrane oxygenation; CPR: Cardiopulmonary resuscitation.

Table 2 Mortality associated with intensive care admission in coronavirus disease 2019

Ref.	Died	Sent home	Total patients	Mortality
Bhatraju et al[6]	12	5	24	50.0%
Arentz et al[22]	11		21	52.4%
Cai et al[23]	3		30	10.0%
Cao et al[24]	6	12	18	33.3%
Chen et al[25]	2		22	9.1%
Grasselli et al[26]	405		1581	25.6%
Han et al[27]	3	12	15	20.0%
Huang et al[28]	5	7	13	38.5%
Intensive Care National Audit and Research Centre[29]	2497		7542	33.1%
Li et al[30]	4		8	50.0%
Ling et al[31]	1	1	8	12.5%
Wang et al[32]	6	9	36	16.7%
Wang et al[33]	7		11	63.6%
Wang et al[34]	133	185	344	38.7%
Wu et al[35]	44		53	83.0%
Yang et al[36]	20		52	38.5%
Zhou et al[37]	39	11	50	78.0%
Total	3198	242	9828	32.5% (average)

Table 3 Mortality associated with endotracheal intubation in coronavirus disease 2019

Ref.	Died	Total patients	Mortality
Bhatraju et al[6]	9	18	50.0%
Cai et al[23]	3	30	10.0%
Cao et al[24]	12	14	33.3%
Intensive Care National Audit and Research Centre[29]	2175	3508	33.1%
Li et al[30]	4	8	50.0%
Ling et al[31]	1	6	12.5%
Wang et al[32]	6	17	35.2%
Wang et al[34]	97	10	38.7%
Wu et al[35]	44	67	83.0%
Yang et al[36]	19	22	38.5%
Zhou et al[37]	31	32	78.0%
Deng et al[38]	21	21	100.00%
Grein et al[39]	6	34	17.6%
Total	2428	3787	64.1% (average)

Table 4 Mortality associated with hemodialysis in coronavirus disease 2019

Ref.	Died	Total patients	Mortality
Cao et al[24]	5	6	83.3%
Intensive Care National Audit and Research Centre[29]	870	1163	74.8%
Wang et al[33]	5	5	100.0%
Yang et al[36]	8	9	88.9%
Zhou et al[37]	10	10	100.0%
Total	898	1193	75.3% (average)