Helicobacter pylori and gastric cardia cancer: What do we know about their relationship?

doi:10.13105/wjma.v8.i2.89

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World Journal of Meta-Analysis

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2308-3840

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Meta-Anal. Apr 28, 2020; 8(2): 89-97
Published online Apr 28, 2020. doi: 10.13105/wjma.v8.i2.89

Helicobacter pylori and gastric cardia cancer: What do we know about their relationship?

Jing-Jing Yin, Fu-Jiao Duan, Sailaja Vatsalya Madhurapantula, Yue-Hua Zhang, Gui He, Kun-Yan Wang, Xuan-Ke Ji, Kai-Juan Wang

Jing-Jing Yin, Fu-Jiao Duan, Sailaja Vatsalya Madhurapantula, Yue-Hua Zhang, Gui He, Kun-Yan Wang, Xuan-Ke Ji, Kai-Juan Wang, Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, Henan Province, China

Jing-Jing Yin, Fu-Jiao Duan, Sailaja Vatsalya Madhurapantula, Yue-Hua Zhang, Gui He, Kun-Yan Wang, Xuan-Ke Ji, Kai-Juan Wang, Key Laboratory of Tumor Epidemiology of Henan Province, Zhengzhou 450052, Henan Province, China

Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, manuscript drafting, critical revision, and editing, and approval of the final version.

Conflict-of-interest statement: The authors declare no conflict of interests for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

Corresponding author: Kai-Juan Wang, MD, PhD, Professor, Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, No. 100, Kexue Avenue, Zhengzhou 450001, Henan Province, China. kjwang@163.com

Received: December 27, 2019
Peer-review started: December 27, 2019
First decision: January 19, 2020
Revised: February 8, 2020
Accepted: March 19, 2020
Article in press: March 19, 2020
Published online: April 28, 2020

Core Tip

Core tip: The relationship between gastric cardia cancer and Helicobacter pylori (H. pylori) is unclear. Therefore, this article focuses on the relationship between gastric cardia cancer and H. pylori and the reasons for this relationship. This paper also discusses the relationship between cagA and gastric cardia cancer, as well as the influence of different colonization sites of H. pylori on gastric cardia cancer and the influence of H. pylori on the prognosis of gastric cardia cancer, and such.