Bowen’s disease on the palm: A case report

Figure 1 A dark red erythematic area 2. 1 cm × 3.0 cm in size and irregular in shape was observed on the thenar eminence of the left palm, with desquamation on the surface and a clear lesion boundary.

Figure 2 Dermatological features of Bowen's disease. A and B: Dermoscopy revealed a clear, scaly, reddish-brown background with glomerular vessels and a scaly surface.

Figure 3 Pathohistological features of Bowen’s disease. A and B: Tissue sections stained with hematoxylin and eosin (A: 100×; B: 200×). Histological characteristics in representative images include hyperkeratosis and parakeratosis, atypical keratinocytes throughout the epidermis, most mitotic phases, disordered cell arrangement, and dyskeratotic cells; additionally, some keratinocytes were vacuolated. A moderate amount of inflammatory infiltrate was present in the upper dermis, which is consistent with Bowen’s disease.

Figure 4 Six months after surgery.