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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2023; 11(26): 6223-6230
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6223
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6223
Typical Zollinger-Ellison syndrome-atypical location of gastrinoma and absence of hypergastrinemia: A case report and review of literature
Jin-Ming Zhang, Chu-Wei Zheng, Zhi-Yun Fang, Hai-Yan Shen, Xia Ji, Department of Gastroenterology, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314001, Zhejiang Province, China
Xiao-Wen Li, Department of Pathology, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314001, Zhejiang Province, China
Mu-Xin Yu, College of Medicine, Jiaxing University, Jiaxing 314001, Zhejiang Province, China
Author contributions: Zhang JM was responsible for writing the paper; Zheng CW was responsible for patient treatment and study design; Fang ZY, Li XW and Yu MX were responsible for collecting and analyzing data; Shen HY and Ji X were responsible for patient follow-up.
Supported by National Natural Science Foundation of China , No. 82100612 ; and Zhejiang Medical Health Science and Technology Plan Project , No. 2021KY1116 .
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and all accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xia Ji, MD, Chief Physician, Department of Gastroenterology, The Second Affiliated Hospital of Jiaxing University, No. 1518 North Round-City Road, Nanhu District, Jiaxing 314001, Zhejiang Province, China. jixia1234@163.com
Received: May 18, 2023
Peer-review started: May 18, 2023
First decision: June 13, 2023
Revised: June 25, 2023
Accepted: August 11, 2023
Article in press: August 11, 2023
Published online: September 16, 2023
Peer-review started: May 18, 2023
First decision: June 13, 2023
Revised: June 25, 2023
Accepted: August 11, 2023
Article in press: August 11, 2023
Published online: September 16, 2023
Core Tip
Core Tip: We recommend gastrinoma as one possible diagnosis for patients presenting Zollinger–Ellison syndrome-like clinical features, but without any typical tumor location or with normal serum gastrin levels. 18F-AlF-NOTA-octreotide positron emission tomography/computed tomography is an advanced imaging technique that can be used to locate and diagnose gastrinoma in such patients.