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For: Jiang W, Guo MH, Hai X. Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat. World J Gastroenterol 2016; 22(46): 10180-10188 [PMID: 28028366 DOI: 10.3748/wjg.v22.i46.10180]
URL: https://www.wjgnet.com/2307-8960/full/v22/i46/10180.htm
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Heibatullah Kalantari, Hossein Foruozandeh, Mohammad Javad Khodayar, Amir Siahpoosh, Najmaldin Saki, Parvin Kheradmand. Antioxidant and hepatoprotective effects of Capparis spinosa L. fractions and Quercetin on tert-butyl hydroperoxide- induced acute liver damage in miceJournal of Traditional and Complementary Medicine 2018; 8(1): 120 doi: 10.1016/j.jtcme.2017.04.010
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Xiaoxia Jiang, Yafeng Zhou, Yun Zhang, Diying Tian, Su Jiang, Yunping Tang. Hepatoprotective effect of pyrroloquinoline quinone against alcoholic liver injury through activating Nrf2-mediated antioxidant and inhibiting TLR4-mediated inflammation responsesProcess Biochemistry 2020; 92: 303 doi: 10.1016/j.procbio.2020.01.023
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Pedro Ferreira-Santos, Rosalía Carrón, M. José Montero, M. Ángeles Sevilla. The antihypertensive and antihypertrophic effect of lycopene is not affected by and is independent of ageJournal of Functional Foods 2021; 85: 104656 doi: 10.1016/j.jff.2021.104656
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Laura Elvira-Torales, Inmaculada Navarro-González, Rocío González-Barrio, Gala Martín-Pozuelo, Guillermo Doménech, Juan Seva, Javier García-Alonso, María Periago-Castón. Tomato Juice Supplementation Influences the Gene Expression Related to Steatosis in RatsNutrients 2018; 10(9): 1215 doi: 10.3390/nu10091215
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Laura Inés Elvira-Torales, Inmaculada Navarro-González, Joaquín Rodrigo-García, Juan Seva, Javier García-Alonso, María Jesús Periago-Castón. Consumption of Spinach and Tomato Modifies Lipid Metabolism, Reducing Hepatic Steatosis in RatsAntioxidants 2020; 9(11): 1041 doi: 10.3390/antiox9111041
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Yaoxiang Zhu, Ruijue Liu, Zhenglin Shen, Guoqiang Cai. Combination of luteolin and lycopene effectively protect against the “two-hit” in NAFLD through Sirt1/AMPK signal pathwayLife Sciences 2020; 256: 117990 doi: 10.1016/j.lfs.2020.117990
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Tarfa Albrahim. Lycopene Modulates Oxidative Stress and Inflammation in Hypercholesterolemic RatsPharmaceuticals 2022; 15(11): 1420 doi: 10.3390/ph15111420
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Ashraf B. Abdel-Naim, Emad H.M. Hassanein, Lenah S. Binmahfouz, Amina M. Bagher, Rawan H. Hareeri, Mardi M. Algandaby, Yousef A.J. Fadladdin, Lotfi Aleya, Mohamed M. Abdel-Daim. Lycopene attenuates chlorpyrifos-induced hepatotoxicity in rats via activation of Nrf2/HO-1 axisEcotoxicology and Environmental Safety 2023; 262: 115122 doi: 10.1016/j.ecoenv.2023.115122
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Jelena Mustra Rakic, Chun Liu, Sudipta Veeramachaneni, Dayong Wu, Ligi Paul, Lynne M. Ausman, Xiang-Dong Wang. Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferretsThe Journal of Nutritional Biochemistry 2021; 91: 108596 doi: 10.1016/j.jnutbio.2021.108596
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Lin Li, Yun-Feng Zhou, Yan-Lin Li, Li-Li Wang, Hiderori Arai, Yang Xu. <i>In vitro</i> and <i>in vivo</i> antioxidative and hepatoprotective activity of aqueous extract of Cortex DictamniWorld Journal of Gastroenterology 2017; 23(16): 2912-2927 doi: 10.3748/wjg.v23.i16.2912
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Jia-Min Yang, Yan Sun, Min Wang, Xin-Lei Zhang, Shu-Jing Zhang, Yu-Shan Gao, Lin Chen, Meng-Yao Wu, Lu Zhou, Yu-Mei Zhou, Yue Wang, Feng-Jie Zheng, Yu-Hang Li. Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver diseaseWorld Journal of Gastroenterology 2019; 25(34): 5105-5119 doi: 10.3748/wjg.v25.i34.5105
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Dongjian Chen, Chao Huang, Zhuo Chen. A review for the pharmacological effect of lycopene in central nervous system disordersBiomedicine & Pharmacotherapy 2019; 111: 791 doi: 10.1016/j.biopha.2018.12.151
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Manar A. Selim, Sarah M. Mosaad, Norhan M El-Sayed. Lycopene protects against Bisphenol A induced toxicity on the submandibular salivary glands via the upregulation of PPAR-γ and modulation of Wnt/β-catenin signalingInternational Immunopharmacology 2022; 112: 109293 doi: 10.1016/j.intimp.2022.109293
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Lina Baz, Salha Algarni, Mona Al-thepyani, Abdullah Aldairi, Hana Gashlan. Lycopene Improves Metabolic Disorders and Liver Injury Induced by a Hight-Fat Diet in Obese RatsMolecules 2022; 27(22): 7736 doi: 10.3390/molecules27227736
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Shanti Bhushan Mishra, Nidhi Kumari. Engineering of Crystalline Nano-Suspension of Lycopene for Potential Management of Oxidative Stress–Linked Diabetes in Experimental AnimalsBioNanoScience 2021; 11(2): 345 doi: 10.1007/s12668-021-00843-4
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Sonal Datta, Diwakar Aggarwal, Nirmala Sehrawat, Mukesh Yadav, Varruchi Sharma, Ajay Sharma, Abdulrazzaq N. Zghair, Kuldeep Dhama, Aanchal Sharma, Vikas Kumar, Anil K. Sharma, Hailian Wang. Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectivesPhytomedicine 2023; 121: 155100 doi: 10.1016/j.phymed.2023.155100
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Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen. Periportal steatosis in mice affects distinct parameters of pericentral drug metabolismScientific Reports 2022; 12(1) doi: 10.1038/s41598-022-26483-6
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Hongmei Chang, Li Li, Yaxin Deng, Guanling Song, Yan Wang. Protective effects of lycopene on TiO2 nanoparticle‐induced damage in the liver of miceJournal of Applied Toxicology 2023; 43(6): 913 doi: 10.1002/jat.4433
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Haeng Hur, Yeon-Hui Jeong, Sang Lee, Mi Sung. Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized MiceLife 2020; 10(10): 243 doi: 10.3390/life10100243
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Kefeng Zhang, Qiongmei Xu, Ya Gao, Houkang Cao, Yuanyu Lian, Zimeng Li, Jie Xu, Mingli Zhong, Jiani Li, Riming Wei, Jianghui Dong, Ling Jin. Polysaccharides from Dicliptera chinensis ameliorate liver disturbance by regulating TLR‐4/NF‐κB and AMPK/Nrf2 signalling pathwaysJournal of Cellular and Molecular Medicine 2020; 24(11): 6397 doi: 10.1111/jcmm.15286
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Tunyu Jian, Yuexian Wu, Xiaoqin Ding, Han Lv, Li Ma, Yuanyuan Zuo, Bingru Ren, Lei Zhao, Bei Tong, Jian Chen, Weilin Li. A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cellsBiomedicine & Pharmacotherapy 2018; 97: 1125 doi: 10.1016/j.biopha.2017.11.043
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Ludovico Abenavoli, Anna Caterina Procopio, Maria Rosaria Paravati, Giosuè Costa, Nataša Milić, Stefano Alcaro, Francesco Luzza. Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver DiseaseJournal of Clinical Medicine 2022; 11(12): 3477 doi: 10.3390/jcm11123477
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Laura Inés Elvira-Torales, Javier García-Alonso, María Jesús Periago-Castón. Nutritional Importance of Carotenoids and Their Effect on Liver Health: A ReviewAntioxidants 2019; 8(7): 229 doi: 10.3390/antiox8070229
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Fayiz M. Reda, Mahmoud Madkour, Nafisa Abd El-Azeem, Osama Aboelazab, Sarah Y.A. Ahmed, Mahmoud Alagawany. Tomato pomace as a nontraditional feedstuff: productive and reproductive performance, digestive enzymes, blood metabolites, and the deposition of carotenoids into egg yolk in quail breedersPoultry Science 2022; 101(4): 101730 doi: 10.1016/j.psj.2022.101730
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Wenya Meng, Zitong Zhao, Lingli Chen, Suyun Lin, Yang Zhang, Jing He, Kehui Ouyang, Wenjun Wang. Total Flavonoids from Chimonanthus nitens Oliv. Leaves Ameliorate HFD-Induced NAFLD by Regulating the Gut–Liver Axis in MiceFoods 2022; 11(14): 2169 doi: 10.3390/foods11142169
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Xiaolei Fang, Jiayu Song, Kaixuan Zhou, Xue Zi, Bin Sun, Huiwei Bao, Lijing Li. Molecular Mechanism Pathways of Natural Compounds for the Treatment of Non-Alcoholic Fatty Liver DiseaseMolecules 2023; 28(15): 5645 doi: 10.3390/molecules28155645
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Jungang Kang, Yang Li, Zhanfei Ma, Yabo Wang, Weifeng Zhu, Guojun Jiang. Protective effects of lycopene against zearalenone-induced reproductive toxicity in early pregnancy through anti-inflammatory, antioxidant and anti-apoptotic effectsFood and Chemical Toxicology 2023; 179: 113936 doi: 10.1016/j.fct.2023.113936
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Huantian Cui, Yuting Li, Min Cao, Jiabao Liao, Xiangguo Liu, Jing Miao, Hui Fu, Ruiwen Song, Weibo Wen, Zhaiyi Zhang, Hongwu Wang. Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver DiseaseFrontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.00858
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Samar Kamel, Dalia W. Zeidan, Howayda E. Khaled, Zinab Abd- Elhady Ali, Nadia G. Elrefaei, Mohamed S. El-Naggar. In Vivo Assessment of Lycopene Effect on Obesity-Induced InflammationBiomedical and Pharmacology Journal 2022; 15(3): 1551 doi: 10.13005/bpj/2493
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Krista Christensen, Thomas Lawler, Julie Mares. Dietary Carotenoids and Non-Alcoholic Fatty Liver Disease among US Adults, NHANES 2003–2014Nutrients 2019; 11(5): 1101 doi: 10.3390/nu11051101
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Charles Oluwaseun Adetunji, Muhammad Akram, Andrew G. Mtewa, Jaison Jeevanandam, Chukwuebuka Egbuna, Alloysius Chibuike Ogodo, Ajay Kumar Gautam, Ashutosh Gupta, Peculiar Feenna Onyekere, Genevieve D. Tupas, Shahira M. Ezzat, Sunil Pareek, Habibu Tijjani, Nadia Sharif, Devaraj Ezhilarasan, Sadia Hassan, Narashans Alok Sagar, Abeer M. El Sayed, Mohammad Mehdizadeh, Merve Keskin, Chioma Obianuju Peculiar-Onyekere, Angelo Mark P. Walag, Priyanka Dhar, Abolanle A.A. Kayode, Ghulam Mohiudin, Khalil Ahmad, Shashank Kumar, Rida Zainab, Muhammad Kamran Khan, Muhammad Adil Farooq, Lisbeth Vallecilla-Yepez, Yusuf Abubakar, Ahmed Olatunde. Preparation of Phytopharmaceuticals for the Management of Disorders2021; : 307 doi: 10.1016/B978-0-12-820284-5.00015-0
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Jia Wang, Ting Li, Mengling Li, Zhendong Fu, Likai Chen, Dongxing Shi, Fubin Qiu, Xintong Tan. Lycopene attenuates oxidative stress-induced hepatic dysfunction of insulin signal transduction: involvement of FGF21 and mitochondriaThe Journal of Nutritional Biochemistry 2022; 110: 109144 doi: 10.1016/j.jnutbio.2022.109144
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Qingwei Meng, Yiming Zhang, Jibo Li, Baoming Shi, Qingquan Ma, Anshan Shan. Lycopene Affects Intestinal Barrier Function and the Gut Microbiota in Weaned Piglets via Antioxidant Signaling RegulationThe Journal of Nutrition 2022; 152(11): 2396 doi: 10.1093/jn/nxac208
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Małgorzata Grabowska, Dariusz Wawrzyniak, Katarzyna Rolle, Piotr Chomczyński, Stefan Oziewicz, Stefan Jurga, Jan Barciszewski. Let food be your medicine: nutraceutical properties of lycopeneFood & Function 2019; 10(6): 3090 doi: 10.1039/C9FO00580C
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Yi Zhao, Ling-Ge Cui, Milton Talukder, Jia-Gen Cui, Hao Zhang, Jin-Long Li. Lycopene prevents DEHP-induced testicular endoplasmic reticulum stress via regulating nuclear xenobiotic receptors and unfolded protein response in miceFood & Function 2021; 12(24): 12256 doi: 10.1039/D1FO02729H
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Saied Mohammadzadeh, Ali Kiani, Mosayeb Amiri. Lycopene modulates hepatic toxicity and testicular injury induced by etoposide in male ratsF&S Science 2023; 4(1): 30 doi: 10.1016/j.xfss.2022.07.005
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Jia Wang, Ting Li, Mengling Li, Dongxing Shi, Xintong Tan, Fubin Qiu. Lycopene attenuates d-galactose-induced insulin signaling impairment by enhancing mitochondrial function and suppressing the oxidative stress/inflammatory response in mouse kidneys and liversFood & Function 2022; 13(14): 7720 doi: 10.1039/D2FO00706A
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Dilek Çavuşoğlu, Tuğçe Kalefetoğlu Macar, Oksal Macar, Emine Yalçın, Kültiğin Çavuşoğlu. Extenuating role of lycopene against 254-nm UV-C radiation-mediated damages in Allium cepa L. rootsEnvironmental Science and Pollution Research 2021; 28(34): 47429 doi: 10.1007/s11356-021-14047-6
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Yi Zhao, De-Xing Ma, Hong-Guang Wang, Mu-Zi Li, Milton Talukder, Hao-Ran Wang, Jin-Long Li. Lycopene Prevents DEHP-Induced Liver Lipid Metabolism Disorder by Inhibiting the HIF-1α-Induced PPARα/PPARγ/FXR/LXR SystemJournal of Agricultural and Food Chemistry 2020; 68(41): 11468 doi: 10.1021/acs.jafc.0c05077
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Monique de Barros Elias, Felipe Leite Oliveira, Fatima Costa Rodrigues Guma, Renata Brum Martucci, Radovan Borojevic, Anderson Junger Teodoro. Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signalingFood & Function 2019; 10(4): 1974 doi: 10.1039/C8FO02369G
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Pedro Ferreira-Santos, Rubén Aparicio, Rosalía Carrón, M. Ángeles Sevilla, José Monroy-Ruiz, M. José Montero. Lycopene-supplemented diet ameliorates cardiovascular remodeling and oxidative stress in rats with hypertension induced by Angiotensin IIJournal of Functional Foods 2018; 47: 279 doi: 10.1016/j.jff.2018.06.002
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Nermeen Mohammed Faheem, Ahmad EL Askary, Amal F. Gharib. Lycopene attenuates bisphenol A–induced lung injury in adult albino rats: a histological and biochemical studyEnvironmental Science and Pollution Research 2021; 28(35): 49139 doi: 10.1007/s11356-021-14140-w
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Hang-Yu Li, Ren-You Gan, Ao Shang, Qian-Qian Mao, Quan-Cai Sun, Ding-Tao Wu, Fang Geng, Xiao-Qin He, Hua-Bin Li, Guodong Zhang. Plant-Based Foods and Their Bioactive Compounds on Fatty Liver Disease: Effects, Mechanisms, and Clinical ApplicationOxidative Medicine and Cellular Longevity 2021; 2021: 1 doi: 10.1155/2021/6621644
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Asmaa Elsayed, Ashraf Elkomy, Reda Elkammar, Gehan Youssef, Ehab Yahya Abdelhiee, Walied Abdo, Sabreen Ezzat Fadl, Ahmed Soliman, Mohamed Aboubakr. Synergistic protective effects of lycopene and N-acetylcysteine against cisplatin-induced hepatorenal toxicity in ratsScientific Reports 2021; 11(1) doi: 10.1038/s41598-021-93196-7
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Irfan Shahid, Kashif Maqbool Khan, Tahir Mehmood Khan, Muhammad Saeed Imran, Nabeel Shahid, Farah Nofal Alnafoosi, Mirza Rafi Baig, Yaser Mohammed Al-Worafi. Clinical Efficacy of LivPro® Herbal Medicine among Hepatitis C Patients Pakistan: Longitudinal Interventional StudyArchives Of Pharmacy Practice 2021; 12(4): 54 doi: 10.51847/v5lmbrLQNQ
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Fawziah A.Al-Salmi. Ameliorative and Synergistic Effect of Red Raspberry and Lycopene Against Hepatotoxicity Induced by Acrylamide in Male MiceInternational Journal of Pharmacology 2019; 15(2): 166 doi: 10.3923/ijp.2019.166.176
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