Rikkunshito increases peripheral incretin-hormone levels in humans and rats

Table 1 Clinicopathological characteristics, n (%)

Variable		TJ-43− (n = 20)	TJ-43+ (n = 21)	P value
Age	Year	67 7.0	66 7.7	0.962
Sex	Male	10 (50)	14 (67)	0.199
	Female	10 (50)	7 (33)
Disease	Pancreas Ca. (Ph)	7 (35)	8 (38)
	IPMC	2 (10)	2 (10)
	IPMA	2 (10)	1 (5)
	CBD Ca.	5 (25)	5 (24)
	Vater Ca.	3 (15)	4 (19)
	Panaceas-NET	1 (5)	0 (0)
	GB Ca.	0 (0)	1 (5)
UICC tumor stage; pancreas Ca. (0/I/IIA/IIB); other Ca. (0/I/II/III)	Pancreas Ca. (Ph)	(0/0/1/6)	(0/0/3/5)
	IPMC	(1/0/1/0)	(0/0/1/1)
	IPMA	N/A	N/A
	CBD Ca.	(0/1/4/0)	(0/3/2/0)
	Vater Ca.	(0/1/2/0)	(0/2/2/0)
	P-NET	(0/1/0/0)	N/A
	GB Ca.	N/A	(0/0/1/0)
Tumor differentiation (well/mod./poor)	Pancreas Ca. (Ph)	(3/2/2)	(1/6/1)
	IPMC	(0/2/0)	(1/0/1)
	IPMA	N/A	N/A
	CBD Ca.	(0/5/0)	(2/2/1)
	Vater Ca.	(2/1/0)	(1/3/0)
	P-NET	N/A	N/A
	GB Ca.	N/A	(0/1/0)
Time of operation	Min	500 ± 56	509 ± 0.72	0.299
Blood loss	mL	692 ± 0.54	959 ± 0.66	0.182
HbA1c	%	5.6 ± 2.2	5.7 ± 2.3	0.892
Tumor markers	CEA (ng/mL)	3.1 ± 1.3	3.7 ± 1.1	0.872
	CA19-9 (U/mL)	455 ± 23	451 ± 29
DGE	%	25	19	0.773
POPF				0.886
Grade A		15 (75)	16 (76)
Grades B and C		5 (25)	5 (24)
Postoperative pneumonia		1 (5)	1 (4.8)	0.889

UICC: Union for International Cancer Control; Ph: Pancreas head; IPMC: Intraductal papillary mucinous carcinoma; IPMA: Intraductal papillary mucinous adenoma; CBD: Common bile duct; Ca.: Carcinoma; NET: Neuroendocrine tumor; GB: Gall bladder; Hb: Hemoglobin; DGE: Delayed gastric emptying; POPF: Postoperative pancreatic fistula; N/A: Not applicable; TJ-43: Rikkunshito.