Forkhead box protein A2 and T helper type 2-mediated pulmonary inflammation

doi:10.5662/wjm.v5.i4.223

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Dec 26, 2015; 5(4): 223-229
Published online Dec 26, 2015. doi: 10.5662/wjm.v5.i4.223

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Figure 1 Structure of forkhead box protein A2 protein. FOXA2 has two transactivation domains and two nuclear localization sequences. There is a winged helix in the central of FOXA2. FOXA: Forkhead box protein A; TAD: Transcription activation domain; NLS: Nuclear localization sequences.

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Figure 2 Network of forkhead box protein A2 regulating T helper type 2 inflammation and goblet cell hyperplasia. IL: Interleukin; mDC: Myeloid dendritic cell; CCL: Chemokine (C-C motif) ligand; Stat6: Signal transducers and activators of transcription 6; PLA2: Phosolipase A2; HPETE: Hydroperoxyeicosatetraenoic acid; LTs: Leukotrienes; MUC: Mucin; FOXA: Forkhead box protein A; Gcnt3: Glucosaminyl (N-Acetyl) transferase 3.

Citation: Sun L, Tang XJ, Luo FM. Forkhead box protein A2 and T helper type 2-mediated pulmonary inflammation. World J Methodol 2015; 5(4): 223-229
URL: https://www.wjgnet.com/2222-0682/full/v5/i4/223.htm
DOI: https://dx.doi.org/10.5662/wjm.v5.i4.223