Residual urinary output in high body mass index individuals on chronic hemodialysis: A disregarded life vest?

Table 1 Patient characteristics n (%)

Variable	Group A	Group B	Group C
N	22	15	20
Male gender	10 (45)	9 (60)	14 (70)
Diabetics	4 (18)	3 (20)	10 (50)
Hypertensives	15 (68)	12 (80)	17 (85)
Median age (yr)	65	71	63
Range	36-83	26-88	33-79
Median time on HD (mo)	12	26	15.5
Range	4-101	9-92	4-55
BMI (Mean ± SD) (kg/m2)	21.3 ± 2.4b	27.6 ± 1.4b	33.9 ± 4.2b
Median MIS	5.5	4	3
Range	1-21	2-8	0-13
Causes of ESRD
Glomerulonephritis	8	7	11
Diabetes	2	2	3
Nephroangiosclerosis	7	3	4
Obstructive uropathy	1	0	1
Interstitial nephritis	1	1	1
Polycystic kidney disease	3	2	0
Median C-Reactive protein (mg/dL)	1.2	1.1	1.1
Range	0.50-12	0.20-8	0-4.5
Median urinary output (mL/d)	690	660	840
Range	140-1780	160-1800	140-2840
Median initial urinary output (mL/d)	790	800	890
Range	170-1860	180-1970	940-2900
Median albumin (g/dL)	3.70a	3.8	3.85a
Range	2.2-4.9	3.2-4.4	3.4-4.9

^bP = 0.001,

^aP = 0.02. MIS: Malnutrition Inflammatory Score; ESRD: End-stage renal disease; HD: Hemodialysis.

Table 2 Blood measurements and ultrafiltration rates in all groups

Group	TropT (ng/mL)	UF rates (L)	Pro-BNP (pg/mL)	Insulin (μU/mL)	HOMA	Leptin (ng/mL)
GA	40	2	4970	7.00ab	1.30cb	3.81bd
	(9-1081)	(0.8-4)	(216-234000)	(2-44)	(0.3-22.4)	(0.8-69.6)
GB	48	2.5	2180	11.50a	2.50c	18.60d
	(5-179)	(0.8-4)	(226-102000)	(4-38)	(1.10-9.30)	(4.7-47.40)
GC	41	3	2040	19.50b	3.75b	32.80b
	(4-186)	(0.5-4.0)	(139-166000)	(5.0-155.0)	(1.0-59.3)	(0.78-124.80)

^aP = 0.02;

^bP = 0.0001;

^cP = 0.03;

^dP = 0.01. UF: Ultrafiltration; Pro-BNP: Pro-brain natriuretic peptide.

Table 3 Different correlations in Groups A and C

	GA BMI <25	GC BMI >30
VARIABLE	ρ; P	ρ; P
Insulin-ultrafiltration rate	0.21; 0.44	0.53; 0.03
TroponinT-diuresis	-0.46; 0.07	-0.48; < 0.05
Pro-BNP-diuresis	-0.43; 0.09	-0.39; < 0.01
TroponinT-proBNP	0.44; 0.09	0.77; < 0.0001
Albumin-TropT	-0.04; 0.87	-0.66; < 0.0001
Albumin-proBNP	-0.1; 0.72	-0.44; < 0.05
Leptin-insulin	0.34; 0.26	0.52; < 0.03

Pro-BNP: Pro-brain natriuretic peptide.