Increasing the use of biocompatible, glucose-free peritoneal dialysis solutions

Figure 1 Continuous Glucose monitoring (6 d) of a Diabetic patient on peritoneal dialysis using Extraneal at night (22:00 to 06:00) not only showing hyperglycemia during the day (after 10 am) when glucose peritoneal dialysis solutions used, but also showing significant and regular episodes of hypoglycemia (unaware) suffered by the patient overnight. Continuous Glucose Monitoring demonstrates the merits and risk of using non-glucose based PD solutions (Extraneal). On one hand the overnight Extraneal dwell (from 22:00 to 06:00 h the next day) controlled the blood sugar effectively in comparison to the glucose based PD fluid dwell (from 06:00 till 22:00 h the same day). On the other hand Extraneal is putting the patient at risk of hypoglycemia (between 05:00 and 08:00 h). It is noteworthy that diabetic end stage renal disease patients have an increase incidence of hypoglycemia unawareness. PD: Peritoneal dialysis.