Immunoglobulin A vasculitis nephritis: Current understanding of pathogenesis and treatment

doi:10.5527/wjn.v12.i4.82

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Sep 25, 2023 (publication date) through Nov 26, 2024

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Sep 25, 2023; 12(4): 82-92
Published online Sep 25, 2023. doi: 10.5527/wjn.v12.i4.82

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Figure 1 Pathogenesis and drug treatment for immunoglobulin A vasculitis and nephritis. Gd-IgA1: Galactose-deficient-immunoglobulin A; AECA: Anti-endothelial cell antibodies; RAAS: Renin-angiotensin-aldosterone system; ACEI: Angiotensin-converting enzyme inhibitors; ARBs: Angiotensin receptor blockers; AZA: Azathioprine; MMF: Mycophenolate mofetil; CsA: Cyclosporine A; CYC: Cyclophosphamide; CNIs: Calcineurin inhibitors.

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Figure 2 Therapeutic algoritm for immunoglobulin A vasculitis and nephritis. ACEI: Angiotensin-converting enzyme inhibitors; ARBs: Angiotensin receptor blockers; IgAVN: Immunoglobulin A vasculitis nephritis; AZA: Azathioprine; MMF: Mycophenolate mofetil; CYC: Cyclophosphamide; CNIs: Calcineurin inhibitors; CsA: Cyclosporine A.

Citation: Amatruda M, Carucci NS, Chimenz R, Conti G. Immunoglobulin A vasculitis nephritis: Current understanding of pathogenesis and treatment. World J Nephrol 2023; 12(4): 82-92
URL: https://www.wjgnet.com/2220-6124/full/v12/i4/82.htm
DOI: https://dx.doi.org/10.5527/wjn.v12.i4.82