Infection related membranoproliferative glomerulonephritis secondary to anaplasmosis: A case report

Figure 1 Kidney Biopsy. A: Light microscopy sections show enlarged glomeruli with lobular accentuation of the capillary loops and both mesangial and endocapillary hypercellularity [periodic acid-Schiff (PAS), 400 ×]; B: Silver-negative, PAS-positive deposits are seen along the capillary loops, resulting in extensive capillary wall remodeling (Jones methenamine silver, 400 ×); C: These deposits show a full-house pattern, highlighting with all immunoglobins and complement components on both standard and pronase immunofluorescence studies (IgG, 400 ×); D and E: On electron microscopy, numerous organized, electron-dense deposits with fibrillary substructure are seen within the mesangial and peripheral capillary loop walls [E: Electron microscopy (EM), 6000 ×], including focal areas with stacked parallel arrays are seen (D: EM, 50000 ×).