Ezigbo ED, Enitan SS, Adejumo EN, Durosinmi AE, Akele RY, Dada MO, Itodo GE, Idoko AM, Edafetanure-Ibeh OM, Okafor EN, Abdulsalam AA, Oyedoyin OI, Yelpoji PU, Opeyemi OO, Nmesomachi OS, Oyekale AO, Onyeji CB. Acceptance of COVID-19 vaccine and its related determinants in Nigeria: An online survey. World J Virol 2024; 13(4): 98551 [DOI: 10.5501/wjv.v13.i4.98551]
Corresponding Author of This Article
Seyi S Enitan, BSc, MSc, Senior Lecturer, Department of Medical Laboratory Science, School of Public and Allied Health, Babcock University, PMB 4003, Ilishan-Remo, OG 121109, Nigeria. enitans@babcock.edu.ng
Research Domain of This Article
Virology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Dec 25, 2024; 13(4): 98551 Published online Dec 25, 2024. doi: 10.5501/wjv.v13.i4.98551
Table 1 Sociodemographic characteristics of the study participants
Variable
Categories
Frequency
Age group in yr
≤ 20
310 (17.2)
21-30
530 (29.4)
31-40
460 (25.6)
41-50
380 (21.1)
> 51
120 (6.7)
Sex
Female
830 (46.1)
Male
970 (53.9)
Location
Rural
170 (9.4)
Urban
1630 (90.6)
Average income
Less than $500 per month
780 (43.3)
$1000-$1999 per month
190 (10.6)
$2000-$2999 per month
240 (13.3)
$3000-$4999 per month
110 (6.1)
$5000-$7999 per month
60 (3.3)
$500-$999 per month
280 (15.6)
$8000-$9999 per month
40 (2.2)
$10000-$12999 per month
30 (1.7)
$13000 or more per month
70 (3.9)
Religion
Catholic
280 (15.6)
Christian/Protestant/Methodist/Lutheran/Baptist
1130 (62.8)
Muslim
380 (21.1)
Other
10 (0.6)
Table 2 Existence of underlying conditions among the study participants
Underlying conditions
Frequency (%)
Have diabetes
150 (8.3)
Have heart disease
40 (2.2)
Have pulmonary disease
20 (1.1)
Have hypertension
0 (0.0)
Table 3 Impacts of the coronavirus disease 2019 pandemic on work and study life of the participants
Variable
Categories
Frequency
Are you currently
Employed for wages
880 (48.9)
Homemaker
10 (0.6)
Out of work for 1 year or more
30 (1.7)
Out of work for less than 1 year
80 (4.4)
Self-employed
150 (8.3)
Student
650 (36.1)
How much has your work changed as a result of the COVID-19 pandemic
I was let go from my job
80 (4.4)
I work fewer hours
340 (18.9)
I work more hours
250 (13.9)
No change. I work the same amount
530 (29.4)
Not applicable (not working)
600 (33.3)
How much has your salary changed as a result of the COVID-19 pandemic
I am getting paid less
660 (36.7)
I am getting paid more
40 (2.2)
No change. I am getting paid the same
1100 (61.1)
In the past week, how often have you gone to work or school outside of the home
0 day
260 (14.4)
1 day
30 (1.7)
2 days
150 (8.3)
3 days
160 (8.9)
4 days
180 (10.0)
5 days
510 (28.3)
6 days
180 (10.0)
7 days
330 (18.3)
Did you wear a mask at work/school
No
20 (1.1)
Not applicable (not going out a whole week)
150 (8.3)
Yes, during my whole time at work/school
1020 (56.7)
Yes, for part of the time at work/school
610 (33.9)
In the past week, how often have you gone to a grocery store or other food vendor
0 day
170 (9.4)
1 day
510 (28.3)
2 days
520 (28.9)
3 days
360 (20.0)
4 days
40 (2.2)
5 days
90 (5.0)
6 days
50 (2.8)
7 days
60 (3.3)
Did you wear a mask at the grocery store or other food vendor
No
130 (7.2)
Not applicable (not going out to grocery store or other food vendor whole week)
80 (4.4)
Yes, during my whole time at the store
1280 (71.1)
Yes, for part of the time at the store
310 (17.2)
Table 4 Perception of vaccination and social distancing measures among the study participants
Variable
Strongly agree
Agree
Neither agree nor disagree
Disagree
Strongly disagree
Vaccines are important for my health
790 (43.9)
780 (43.3)
170 (9.4)
20 (1.1)
40 (2.2)
Vaccines are effective
650 (36.1)
870 (48.3)
240 (13.3)
10 (0.6)
30 (1.7)
Being vaccinated is important for the health of others in my community
860 (47.8)
740 (41.1)
140 (7.8)
50 (2.8)
10 (0.6)
All routine vaccines recommended by the healthcare workers are beneficial
580 (32.2)
850 (47.2)
300 (16.7)
60 (3.3)
10 (0.6)
New vaccines carry more risks than older vaccines
330 (18.3)
490 (27.2)
670 (37.2)
220 (12.2)
90 (5.0)
The information I receive about vaccines from the government is reliable and trustworthy
130 (7.2)
610 (33.9)
770 (42.8)
220 (12.2)
70 (3.9)
Getting vaccines is a good way to protect me from disease
740 (41.1)
820 (45.6)
150 (8.3)
50 (2.8)
40 (2.2)
Generally, I follow vaccine recommendations from my doctor or health care provider
650 (36.1)
950 (52.8)
140 (7.8)
50 (2.8)
10 (0.6)
Social distancing can protect yourself from COVID-19
970 (53.9)
730 (40.6)
70 (3.9)
20 (1.1)
10 (0.6)
Social distancing can protect your child or children from COVID-19
1030 (57.2)
650 (36.1)
100 (5.7)
20 (1.1)
0 (0.0)
Social distancing can protect your parents from COVID-19
1030 (57.2)
670 (37.2)
80 (4.4)
20 (1.1)
0 (0.0)
Table 5 Perception of vaccination and social distancing measures among those with underlying conditions
Variable
Strongly agree
Agree
Neither agree nor disagree
Disagree
Strongly disagree
Vaccines are important for my health
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
Vaccines are effective
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
Being vaccinated is important for the health of others in my community
210 (100)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
All routine vaccines recommended by the healthcare workers are beneficial
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
New vaccines carry more risks than older vaccines
0 (0.0)
20 (9.52)
80 (38.1)
100 (47.6)
10 (4.76)
The information I receive about vaccines from the government is reliable and trustworthy
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
Getting vaccines is a good way to protect me from disease
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
Generally, I follow vaccine recommendations from my doctor or health care provider
200 (95.2)
10 (4.76)
0 (0.0)
0 (0.0)
0 (0.0)
Social distancing can protect yourself from COVID-19
210 (100)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Social distancing can protect your child or children from COVID-19
200 (95.2)
5 (2.38)
5 (2.38)
0 (0.0)
0 (0.0)
Social distancing can protect your parents from COVID-19
200 (95.2)
5 (2.38)
5 (2.38)
0 (0.0)
0 (0.0)
Table 6 Association between sociodemographic and perception of vaccination and social distancing measures among the study participants
Variable
Categories
Poor perception
Good perception
Total
χ²
P value
Odds ratio (95%CI)
Age group (yr)
≤ 20
220 (12.2)
90 (5.0)
310 (17.2)
8.449
0.076
21-30
260 (14.4)
270 (15.0)
530 (29.4)
1.25 (0.94-1.65)
31-40
200 (11.1)
260 (14.4)
460 (25.6)
41-50
160 (8.9)
220 (12.2)
380 (21.1)
> 51
40 (2.2)
80 (4.4)
120 (6.7)
Sex
Female
450 (25.0)
380 (21.1)
830 (46.1)
1.75
0.186
Male
430 (23.9)
540 (30.0)
970 (53.9)
0.74 (0.38-1.44)
Location
Rural
110 (6.1)
60 (3.3)
170 (9.4)
1.88
0.17
Urban
770 (42.8)
860 (47.8)
1630 (90.6)
0.50 (0.16-1.51)
Average income
Less than $500 per month
410 (22.8)
370 (20.6)
780 (43.3)
1.17 (0.14-9.43)
$500-$999 per month
110 (6.1)
170 (9.4)
280 (15.6)
0.94 (0.17-5.27)
$1000-$1999 per month
80 (4.4)
110 (6.1)
190 (10.6)
7.15
0.521
$2000-$2999 per month
110 (6.1)
130 (7.2)
240 (13.3)
0.38 (0.07-2.21)
$3000-$4999 per month
40 (2.2)
70 (3.9)
110 (6.1)
1.19 (0.46-3.10)
$5000-$7999 per month
30 (1.7)
30 (1.7)
60 (3.3)
1.33 (0.34-5.13)
$8000-$9999 per month
20 (1.1)
20 (1.1)
40 (2.2)
1.59 (0.64-3.96)
$10000-$12999 per month
30 (1.7)
0 (0)
30 (1.7)
1.26 (0.44-3.65)
$13000 or more per month
50 (2.8)
20 (1.1)
70 (3.9)
0.00 (0.00-0.00)
Religion
Catholic
150 (8.3)
130 (7.2)
280 (15.6)
2.819
0.42
Christian/Protestant/Methodist/Lutheran/ Baptist
580 (32.2)
550 (30.6)
1130 (62.8)
0.00 (0.00-0.00)
Muslim
150 (8.3)
230 (12.8)
38 (21.1)
0.00 (0.00-0.00)
Other
0 (0.0)
10 (0.6)
1 (0.6)
0.00 (0.00-0.00)
Table 7 Occurrence of the coronavirus disease 2019 and the severity among the study participants
Variable
Categories
Frequency
Diagnosed with COVID-19 by a doctor
No
1700 (94.4)
Yes
100 (5.6)
How serious was the course of illness when you were infected with COVID-19
Not applicable
1700 (94.4)
Not very serious
60 (3.3)
Somewhat serious
40 (2.2)
Do you know people in your immediate social environment (close friends or family members) who are or have been infected with COVID-19
Do not know
420 (23.3)
No
670 (37.2)
Yes
710 (39.4)
How serious was the course of illness when your friend or family member was infected with the COVID-19? If you know multiple people who have had COVID-19, think about the most recent one
Not applicable
1090 (60.6)
Not very serious
260 (14.4)
Somewhat serious
300 (16.7)
Very serious
150 (8.3)
Have you seen or read about individuals infected with the COVID-19 on social media or TV
No
30 (1.7)
Yes
1770 (98.3)
How serious was the course of illness for the most recent COVID-19 case you have seen or read about in social media or on the TV
No idea
30 (1.7)
Not very serious
260 (14.4)
Somewhat serious
620 (34.4)
Very serious
890 (49.4)
Have you ever heard that your local health facilities stop the vaccination service for kids due to COVID-19 pandemic
No
1550 (86.1)
Yes
250 (13.9)
Table 8 Coronavirus disease 2019 vaccine acceptance rates among the study participants
Variable
Categories
Frequency
Imagine that a new COVID-19 vaccine has just been developed. It has received the same testing as the adult influenza vaccine. The government is offering it as a FREE and optional vaccine. Would you accept a COVID-19 vaccine if the vaccine was 95% effective
No
420 (23.3)
Yes
1380 (76.7)
The vaccine is 50% effective, with a 5% chance of a side effect like a fever (50% effective means that there is a 50% reduction in disease among those vaccinated compared to those unvaccinated)
No
860 (47.8)
Yes
940 (52.2)
The vaccine is 95% effective, with a 20% chance of a side effect like a fever (95% effective means that there is a 95% reduction in disease among those vaccinated compared to those unvaccinated)
No
550 (30.6)
Yes
1250 (69.4)
The vaccine is 75% effective, with a 5% chance of a side effect like a fever (75% effective means that there is a 75% reduction in disease among those vaccinated compared to those unvaccinated)
No
400 (22.2)
Yes
1400 (77.8)
The vaccine is 75% effective, with a 20% chance of a side effect like a fever (75% effective means that there is a 75% reduction in disease among those vaccinated compared to those unvaccinated)
No
990 (55.0)
Yes
810 (45.0)
For a COVID-19 vaccine that is 95% effective and a 5% chance of a side effect like fever or local pain? If the price was US$50 for complete vaccination. Would you buy the vaccine and get vaccinated
No
540 (30.0)
Yes
1260 (70.0)
If the COVID-19 vaccine price was US$100. Would you buy the vaccine and get vaccinated
No
650 (36.1)
Yes
1150 (63.9)
If the COVID-19 vaccine price was US$200. Would you still buy the vaccine and get vaccinated
No
570 (31.7)
Yes
1230 (68.3)
If the COVID-19 vaccine price is reduced to US$25. Would you buy the vaccine and get vaccinated
No
550 (30.6)
Yes
1250 (69.4)
If the COVID-19 vaccine price was US$12.5. Would you buy the vaccine and get vaccinated
No
1210 (67.2)
Yes
590 (32.8)
If the COVID-19 vaccine price was US$5 only. Would you buy the vaccine and get vaccinated
No
630 (35.0)
Yes
1170 (65.0)
Table 9 Coronavirus disease 2019 vaccine acceptance rates among those with underlying conditions
Variable
Categories
Frequency
Imagine that a new COVID-19 vaccine has just been developed. It has received the same testing as the adult influenza vaccine. The government is offering it as a free and optional vaccine. Would you accept a COVID-19 vaccine if the vaccine was 95% effective?
No
0 (0.0)
Yes
210 (100.0)
The vaccine was 50% effective, with a 5% chance of a side effect like a fever? (50% effective means that there is a 50% reduction in disease among those vaccinated compared to those unvaccinated)
No
10 (4.8)
Yes
200 (95.2)
The vaccine was 95% effective, with a 20% chance of a side effect like a fever? (95% effective means that there is a 95% reduction in disease among those vaccinated compared to those unvaccinated)
No
30 (14.3)
Yes
180 (85.7)
The vaccine was 75% effective, with a 5% chance of a side effect like a fever? (75% effective means that there is a 75% reduction in disease among those vaccinated compared to those unvaccinated)
No
25 (11.9)
Yes
185 (88.09)
The vaccine was 75% effective, with a 20% chance of a side effect like a fever? (75% effective means that there is a 75% reduction in disease among those vaccinated compared to those unvaccinated)
No
30 (14.3)
Yes
180 (85.7)
For a COVID-19 vaccine that was 95% effective and a 5% chance of a side effect like a fever or local pain? If the price is US$50 for complete vaccination. Would you buy the vaccine and get vaccinated?
No
0 (0.0)
Yes
210 (100)
If the COVID-19 vaccine price was US$100. Would you buy the vaccine and get vaccinated?
No
0 (0.0)
Yes
210 (100.0)
If the COVID-19 vaccine price was US$200. Would you buy the vaccine and get vaccinated?
No
10 (4.8)
Yes
200 (95.2)
If the COVID-19 vaccine price was reduced to US$25. Would you buy the vaccine and get vaccinated?
No
0 (0.0)
Yes
210 (100.0)
If the COVID-19 vaccine price was US$12.5. Would you buy the vaccine and get vaccinated?
No
0 (0.0)
Yes
210 (100.0)
If the COVID-19 vaccine price was US$5 only. Would you buy the vaccine and get vaccinated?
No
0 (0.0)
Yes
210 (100.0)
Table 10 Association between sociodemographic and the coronavirus disease 2019 vaccine acceptance rates among the study participants
Variable
Categories
Poor
Good
Total
χ²
P value
Odds ratio (95%CI)
Age group (yr)
≤ 20
70 (3.9)
240 (13.3)
310 (17.2)
3.049
0.55
21-30
200 (11.1)
330 (18.3)
530 (29.4)
0.76 (0.57-1.02)
31-40
180 (10.0)
280 (15.6)
460 (25.6)
41-50
150 (8.3)
230 (12.8)
380 (21.1)
> 51
50 (2.8)
70 (3.9)
120 (6.7)
Sex
Female
310 (17.2)
520 (28.9)
830 (46.1)
0.102
0.749
Male
340 (18.9)
630 (35.0)
970 (53.9)
0.83 (0.42-1.62)
Location
Rural
60 (3.3)
110 (6.1)
170 (9.4)
0.005
0.941
Urban
590 (32.8)
1040 (57.8)
1630 (90.6)
0.90 (0.29-2.78)
Average income
Less than $500 per month
310 (17.2)
470 (26.1)
780 (43.3)
2.74 (0.25-30.32)
$500-$999 per month
110 (6.1)
170 (9.4)
280 (15.6)
4.14 (0.44-38.90)
$1000-$1999 per month
40 (2.2)
150 (8.3)
190 (10.6)
3.802
0.875
$2000-$2999 per month
90 (5.0)
150 (8.3)
240 (13.3)
0.81 (0.16-4.05)
$3000-$4999 per month
40 (2.2)
70 (3.9)
110 (6.1)
1.25 (0.47-3.29)
$5000-$7999 per month
10 (0.6)
50 (2.8)
60 (3.3)
1.33 (0.34-5.22)
$8000-$9999 per month
10 (0.6)
30 (1.7)
40 (2.2)
1.08 (0.43-2.68)
$10000-$12999 per month
10 (0.6)
20 (1.1)
30 (1.7)
2.76 (0.81-9.42)
$13000 or more per month
30 (1.7)
40 (2.2)
70 (3.9)
1.14 (0.09-13.78)
Religion
Catholic
100 (5.6)
180 (10.0)
280 (15.6)
1.804
0.614
Christian/Protestant/Methodist/Lutheran/Baptist
440 (24.4)
690 (38.3)
1130 (62.8)
0.00 (0.00-0.00)
Muslim
110 (6.1)
270 (15.0)
380 (21.1)
0.00 (0.00-0.00)
Other
0 (0.0)
10 (0.6)
10 (0.6)
0.00 (0.00-0.00)
Table 11 Overall mean score of the coronavirus disease 2019 vaccine acceptance rates among the study participants
Variable
Poor
Good
P value
Overall score on perception of vaccination and social distancing measures among the study participants
8.49 ± 2.72
9.04 ± 1.88
0.112
Overall score on the coronavirus disease 2019 vaccine acceptance rates among the study participants.
4.18 ± 1.66
8.44 ± 1.14
0.000
Citation: Ezigbo ED, Enitan SS, Adejumo EN, Durosinmi AE, Akele RY, Dada MO, Itodo GE, Idoko AM, Edafetanure-Ibeh OM, Okafor EN, Abdulsalam AA, Oyedoyin OI, Yelpoji PU, Opeyemi OO, Nmesomachi OS, Oyekale AO, Onyeji CB. Acceptance of COVID-19 vaccine and its related determinants in Nigeria: An online survey. World J Virol 2024; 13(4): 98551