Human immunodeficiency virus cascade–continuum of care stages and outcomes in a hospital in southern Brazil

Table 1 Analysis of variables with absolute number and relative percentage and Poisson regression with robust simple variance of each variable in relation to the steps of the cascade of patients diagnosed with human immunodeficiency virus in the Nossa Senhora da Conceição Hospital, n (%)/95%CI

	Total	Linked	P value	Retained	P value	On ART	P value	HIV-VL suppressed	P value
Total	534	500 (93.6)		455 (85.2)		368 (68.9)		308 (57.6)
Gender
Female	303 (56.7)	284 (93.7)	0.917	264 (87.1)	0.161	198 (65.3)	0.039	162 (53.5)	0.023
		1.00 (0.95-1.04)		1.05 (0.97-1.13)		0.88 (0.79-0.99)		0.84 (0.73-0.97)
Male	231 (43.3)	216 (93.5)		191 (82,7)		170 (73,6)		146 (63,2)
		1.00		1.00		1.00		1.00
Age (yr)
18-29	154 (28.8)	148 (96.1)	0.252	129 (83.8)	0.420	92 (59.7)	0.000	70 (45.5)	0.000
		1.03 (0.97-1.10)		0.96 (0.86-1.06)		0.73 (0.63-0.86)		0.63 (0.51-0.78)
30-49	270 (50.6)	250 (92.6)	0.964	230 (85.2)	0.585	187 (69.3)	0.012	159 (58.9)	0.011
		0.99 (0.93-1.06)		0.97 (0.89-1.06)		0.85 (0.75-0.96)		0.82 (0.70-0.95)
> 50	110 (20.6)	102 (92.7)		96 (87.3)		89 (80.9)		79 (71.8)
		1.0		1.0		1.0		1.0
Race
White	374 (70.0)	348 (93.0)		319 (85.3)		266 (71.1)		255 (60.2)
		1.0		1.0		1.0		1.0
Not white	160 (30.0)	152 (95.0 )	0.367	136 (85.0)	0.930	102 (63.7)	0.108	83 (51.9)	0.089
		1.02 (0.97-1.06)		0.99 (0.92-1.07)		0.89 (0.78-1.02)		0.86 (0.72-1.02)
Education
Illiterate	16 (3.0)	12 (75)	0.188	11 (68.8)	0.103	9 (56.3)	0.031	7 (43.8)	0.064
		0.80 (0.58-1.11)		0.74 (0.51-1.06)		0.60 (0.38-0.95)		0.55 (0.30-1.03)
Elementary School	367 (68.7)	346 (94.3)	0.840	310 (84.5)	0.221	246 (67.0)	0.000	202 (55.0)	0.016
		1.01 (0.87-1.17)		0.91 (0.78-1.05)		0.72 (0.61-0.84)		0.70 (0.52-0.93)
High School	136 (25.5)	128 (94.1)	0.861	120 (88.2)	0.526	99 (72.8)	0.007	87 (64.0)	0.181
		1.01 (0.87-1.17)		0.95 (0.81-1.11)		0.78 (0.65-0.93)		0.81 (0.60-1.10)
University Education	14 (2.6)	13 (92.9)		13 (92.9)		13 (92.9)		11 (78.6)
		1.0		1.0		1.0		1.0
City of origin
Porto Alegre	370 (69.3)	350 (94.6)		312 (84.3)		249 (67.3)		210 (56.8)
		1.0		1.0		1.0		1.0
Metropolitan region	128 (24.0)	118 (92.2)	0.367	112 (87.5)	0.358	94 (73.4)	0.175	79 (61.7)	0.313
		0.97(0.92-1.03)		1.03 (0.95-1.12)		1.09 (0.96-1.23)		1.08 (0.92-1.28)
Countryside	36 (6.7)	32 (88.9)	0.302	31 (86.1)	0.766	25 (69.4)	0.787	19 (52.8)	0.658
		0.94 (0.83-1.05)		1.02 (0.88-1.17)		1.03 (0.82-1.29)		0.93 (0.67-1.28)
Follow-up site
HNSC	236 (51.8)	236 (100)		225 (95.3)		197 (83.5)		172 (72.9)
		1.0		1.0		1.0		1.0
External	220 (48.2)	219 (99.5)	0.317	209 (95.0)	0.866	169 (76.8)	0.07	135 (61.4)	0.010
		0.99 (0.98-1.00)		0.99 (0.95-1.03)		0.92 (0.83-1.00)		0.84 (0.73-0.95)

P < 0.20 considered significant. ART: Antiretroviral therapy; HIV-VL: Human immunodeficiency virus-viral load; HNSC: Nossa Senhora da Conceição Hospital.

Table 2 Poisson regression analysis with multivariable robust variance in relation to the steps on antiretroviral therapy and human immunodeficiency virus-viral load suppressed of patients diagnosed with human immunodeficiency virus in the Nossa Senhora da Conceição Hospital, 95%CI

	On ART	P value	HIV-VL suppressed	P value
Gender
Female	0.93 (0.85-1.02)	0.163	0.90 (0.80-1.02)	0.126
Male	1.00		1.00
Age (yr)
18-29	0.79 (0.69-0.90)	0.000	0.66 (0.54-0.80)	0.000
30-49	0.90 (0.82-0.99)	0.041	0.87 (0.76-0.99)	0.044
> 50	1.0		1.0
Race
White	1.0		1.0
Not White	0.94 (0.85-1.05)	0.325	0.91 (0.78-1.05)	0.215
Education
Illiterate	0.98 (0.75-1.28)	0.886	1.03 (0.68-1.55)	0.881
Elementary School	0.86 (0.73-1.00)	0.060	0.86 (0.66-1.14)	0.311
High School	0.93 (0.78-1.10)	0.415	1.03 (0.78-1.37)	0.794
University Education	1.0		1.0
City of origin
Porto Alegre	0.96 (0.80-1.15)	0.693
Metropolitan region	1.06 (0.88-1.27)	0.534
Countryside	1.0
Follow-up site
HNSC	1.09 (0.99-1.20)	0.055	1.18 (1.03-1.34)	0.011
External	1.0		1.0

P < 0.05 considered significant. ART: Antiretroviral therapy; HIV-VL: Human immunodeficiency virus-viral load; HNSC: Nossa Senhora da Conceição Hospital.

Table 3 Comparison between patients who underwent follow-up at the Nossa Senhora da Conceição Hospital and external institutions using Pearson’s χ² test, n (%)

	HNSC	External	P value
Total	236	220
Gender			0.217
Female	127 (53.8)	131 (59.5)
Age (yr)			0.057
18-29	70 (29.7)	60 (27.3)
30-49	107 (45.3)	122 (55.5)
> 50	59 (25.0)	38 (17.3)
Race			0.945
White	167 (70.8)	155 (70.5)
Education			0.485
Illiterate	4 (1.7)	5 (2.3)
Elementary School	161 (68.2)	150 (68.5)
High School	61 (25.8)	60 (27.4)
University Education	10 (4.2)	4 (1.8)
City of origin			0.000
Porto Alegre	189 (80.1)	127 (57.7)
Metropolitan region	36 (15.3)	73 (33.2)
Countryside	11 (4.7)	20 (9.1)
Hospital admission	160 (67.8)	161 (73.2)	0.208
Initial CD4+ T-cell count			0.075
0-200 cells/mm3	91 (38.6)	71 (32.4)
201-500 cells/mm3	84 (35.6)	70 (32.0)
> 501 cells/mm3	61 (25.8)	78 (35.6)
Final CD4+ T-cell count			0.518
0-200 cells/mm3	17 (7.6)	20 (9.6)
201-500 cells/mm3	76 (33.8)	61 (29.3)
> 501 cells/mm3	132 (58.7)	127 (61.1)
Number of CD4+ T-cell /HIV-VL samples			0.316
1-3	53 (22.6)	55 (25.2)
4-6	103 (43.8)	104 (47.7)
7 or more	79 (33.6)	59 (27.1)
Number of ART schemes			0.215
1	164 (69.5)	142 (64.5)
2	44 (18.6)	56 (25.5)
> 3	24 (10.2)	21 (9.5)
Time of ART initiation			0.001
Up to 1 month	117 (50.4)	103 (47.0)
1-6 months	94 (40.5)	67 (30.6)
6-12 months	12 (5.2)	24 (11.0)
After 1 year	9 (3.9)	25 (11.4)

P < 0.05 considered significant. ART: Antiretroviral therapy; HIV-VL: Human immunodeficiency virus-viral load; HNSC: Nossa Senhora da Conceição Hospital.