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©The Author(s) 2022.
World J Virol. Nov 25, 2022; 11(6): 485-495
Published online Nov 25, 2022. doi: 10.5501/wjv.v11.i6.485
Published online Nov 25, 2022. doi: 10.5501/wjv.v11.i6.485
Serial no. | Ref. | Reported musculoskeletal complications | Type of study | Types of patients | Rehabilitation intervention |
1 | Ludvigsson[2], 2021 | Fatigue, muscle weakness | Systematic review | Children | No |
2 | Akbarialiabad et al[3], 2021 | Fatigue (63%), muscle weakness | Systematic scoping review | All age groups | No |
3 | Michelen et al[4], 2021 | Weakness (41%; 95%CI: 25%-59%), general malaise (33%; 95%CI: 15%-57%), fatigue (31%; 95%CI: 24%-39%) | Living systematic review | All age groups | No |
4 | Iqbal et al[5], 2021 | 48% fatigue in >12 wk | Systematic review and meta-analysis | All age groups | No |
5 | Vollbracht and Kraft[6], 2021 | Vitamin C improved in post-COVID-19 fatigue; the IV vitamin C doses administered ranged from 3.5 g to > 75 g/d | A systematic review on intervention | All age groups | No |
6 | Jennings et al[7], 2021 | Arthralgia 13% (6%-29%), myalgia 34% (2%-86%), fatigue 44% (10%-71%) | Systematic review | All age groups | No |
7 | Fernández-de-Las-Peñas et al[8], 2021 | Fatigue (58%), headache (44%), joint pain (15%-20%) | Systematic review | All age groups | No |
8 | Malik et al[9], 2022 | Fatigue (64, 54-73), arthralgia (24.3, 14.0-36.0), headache (21, 3-47) | Systematic review and meta-analysis | All age groups | No |
9 | Ceban et al[10], 2022 | Fatigue in 30% of cases | Systematic review and meta-analysis | All age groups | No |
10 | Chen et al[11], 2022 | Fatigue prevalence 0.23 (95%CI: 0.17-0.30) | Systematic review and meta-analysis | All age groups | No |
11 | van Kessel et al[12], 2022 | Fatigue most common | Systematic review | All age groups | No |
12 | Alkodaymi et al[13], 2022 | Fatigue 3-6 mo follow-up 32%, 36% 6-9 mo, 37% 9-12 mo, > 12 mo, 41% | Systematic review | All age groups | No |
13 | Fernández-de-Las-Peñas et al[14], 2022 | Prevalence of post-COVID-19 myalgia, joint pain, and chest pain ranged from 5.65% to 18.15%, 4.6% to 12.1%, and 7.8% to 23.6%, respectively, at different follow-up periods during the 1st yr postinfection. Almost 10% of individuals infected by SARS-CoV-2 will suffer from musculoskeletal post-COVID-19 pain symptomatology at some time during the 1st yr after the infection | Systematic review | All age groups | No |
14 | Han et al[15], 2022 | Fatigue/weakness (28%, 95%CI: 18%-39%), arthromyalgia (26%, 95%CI: 8%-44%) | Systematic review | All age groups | No |
15 | d’Ettorre et al[16], 2022 | 63% of fatigue reported | Systematic review | All age groups | No |
16 | Behnood et al[17], 2022 | 47% fatigue, 25% myalgia, 35% headache, females with higher pain symptoms | Systematic review | In children and young people | No |
17 | Nguyen et al[18], 2022 | Fatigue (16%-64%), arthralgia (8%-55%), thoracic pain (5%-62%), myalgia (1%-22%), headache (9%-15%) | Systematic review | All age groups | No |
18 | Lopez-Leon et al[19], 2022 | Fatigue (9.66%) | Systematic review | Children and adolescents | No |
19 | Abdel-Gawad et al[20], 2022 | Fatigue (72.8%) and joint pain (31.4%) | Systematic review | All age groups | No |
20 | Almas et al[21], 2022 | Fatigue (54.11%), arthralgia (16.35%), myalgia (5.78%), chest pain (10.37%) | Systematic review | All age groups | No |
21 | Maglietta et al[22], 2022 | Fatigue and female sex association statistically significant, with OR = 1.54, 95%CI: 1.32-1.79 | Systematic review | All age groups | No |
22 | Healey et al[23], 2022 | fatigue (37%; 95%CI: 23%-55%), myalgia (12%; 95%CI: 5%-25%), headache (7%; 95%CI: 3%-16%), chest pain (3%; 95%CI: 1%-8%) | Systematic review | All age groups | No |
23 | de Oliveira Almeida et al[24], 2022 | Fatigue. COVID-19 survivors can have a reduction in physical function, ability to perform activities of daily living and their health-related quality of life 1-6 mo post-infection | Systematic review | All age groups | No |
24 | Fugazzaro et al[25], 2022 | Muscle strength, walking capacity, sit-to-stand performance improvements | Systematic review of rehabilitation interventions | All age groups | Yes |
- Citation: Swarnakar R, Jenifa S, Wadhwa S. Musculoskeletal complications in long COVID-19: A systematic review. World J Virol 2022; 11(6): 485-495
- URL: https://www.wjgnet.com/2220-3249/full/v11/i6/485.htm
- DOI: https://dx.doi.org/10.5501/wjv.v11.i6.485