Dipeptidyl peptidase 4 inhibitors in COVID-19: Beyond glycemic control

doi:10.5501/wjv.v11.i6.399

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Nov 25, 2022 (publication date) through Jan 20, 2025

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol. Nov 25, 2022; 11(6): 399-410
Published online Nov 25, 2022. doi: 10.5501/wjv.v11.i6.399

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Figure 1 Proposed mechanisms of dipeptidyl peptidase-4 inhibitors in coronavirus disease 2019 infection. ACE2R: Angiotensin converting enzyme 2 receptor; COVID-19: Coronavirus disease 2019; DPP-4: Dipeptidyl peptidase-4; FOXP3: Forkhead box P3; IL: Interleukin; mDPP4: Membrane bound DPP4; sDPP4: Soluble DPP4; TGF-β: Transforming growth factor beta.

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Figure 2 Hypothetical interactions between dipeptidyl peptidase-4 and severe acute respiratory syndrome coronavirus 2 virus. ACE-2: Angiotensin-converting enzyme 2; ACE2R: Angiotensin converting enzyme 2 receptor; DPP-4: Dipeptidyl peptidase-4; mDPP4: Membrane bound DPP4; sDPP4: Soluble DPP4.

Citation: Narayanan N, Naik D, Sahoo J, Kamalanathan S. Dipeptidyl peptidase 4 inhibitors in COVID-19: Beyond glycemic control. World J Virol 2022; 11(6): 399-410
URL: https://www.wjgnet.com/2220-3249/full/v11/i6/399.htm
DOI: https://dx.doi.org/10.5501/wjv.v11.i6.399