International kidney paired donation transplantations to increase kidney transplant of O group and highly sensitized patient: First report from India

Table 1 Human leukocyte antigen data of patient and donor

	A		B		Bw		Cw		DR B1		DR B3, 4, 5		DQ B1
Patient 1	1	24	15	37	4	6	6	8	10	12	52	-	5	7
Donor 2	1	11	40	-	6	-	15	-	8	11	52	-	7	4
Patient 2	2	33	15	51	6	-	1	12	4	8	53	-	7	8
Donor 1	1	68	15	55	6	-	7	0	7	14	52	53	2	6

Patient 1: Donor specific antibody in mean fluorescence intensity with donor 1, A68 = 9870; B55 = 7736; CW7 = 11600 and no donor specific antibody with donor 2; Patient 2: No donor specific antibody with donor 1 and 2.

Table 2 Demographics and outcome of two way kidney exchange

	Patient 1	Patient 2	Donor 1	Donor 2
Patient data
Age (yr)	40	30
Gender	Male	Female
Original disease - ESRD	Hypertension	Hypertension
ABO blood group	A	O
Dialysis duration (mo)	12	12
Weight (kg)	68	40
Original donor relation	Wife	Husband
Reason for Joining KPD	Sensitized	ABO incompatible
Time from KPD registration to find KPD donor (wk)	2	36
Time from KPD donor to transplant	4 wk	4 wk
Desensitization	No	No
State	Portugal	Rajasthan, India
Donor data
Age (yr)			36	33
Gender			Female	Male
Weight (kg)			60	60
ABO blood group			O	A
Glomerular filtration rate (right/left)			56/54	54/54
Creatinine (mg/ dL)			0.6	0.7
Renal vessel (right/left)			1 artery and vein on each side	1 artery and vein on each side
Laparoscopic donor nephrectomy			Left	Left
Surgical details and outcome
Warm ischemia time (s)			150	117
Cold ischemia time (min)			60	90
Anastomosis time (min)			43	35
Intraoperative urine (mL)			1800	500
Kidney transplant date			17 Feb 2015	17 Feb 2015
Creatinine (mg/dL)			1	1
Follow- up (mo)			11	11

KPD: Kidney paired donation.