Risk factors and outcomes of delayed graft function in renal transplant recipients receiving a steroid sparing immunosuppression protocol

Table 1 Patient demographics

Factor		DGF n = 135 (%)	PGF n = 292 (%)	P value
Recipient age	Years (mean)	51.43 ± 12.19	47.45 ± 13.93	0.0046
Donor age	Years (mean)	51.56 ± 13.05	47.00 ± 15.99	0.0041
Recipient gender	Male	105 (77.8)	178 (61.0)	0.0009
	Female	30 (22.2)	114 (39.0)
Donor gender	Male	69 (51.1)	123 (42.1)	0.12
	Female	66 (48.9)	167 (57.2)
Ethnicity	Black	35 (25.9)	41 (14.0)	0.004
	Non-black	100 (74.1)	251 (86.0)
Time on RRT	Years (mean)	6.37 ± 5.44	5.00 ± 5.07	0.012
Regrafts	1st	114 (84.4)	261 (89.4)	0.2
	> 2nd	21 (15.6)	31 (10.6)
Donation type	DCD	45 (33.3)	32 (11.0)	< 0.00001
	DBD	90 (66.6)	259 (88.7)
CIT	Hours (mean)	24.70 ± 7.82	21.29 ± 7.58	0.000023
HLA mismatch	Mean	3.47 ± 1.30	3.19 ± 1.58	0.079
Preformed DSA	DSA+	17 (12.6)	18 (6.2)	0.039
	DSA-	118 (87.4)	274 (93.8)
Induction	Alemtuzumab	113 (83.7)	292 (84.9)	0.86
	IL2RA	22 (16.3)	44 (15.1)
Recipient Diabetes	Yes	35 (25.9)	46 (15.8)	0.02
	No	100 (74.1)	246 (84.2)

CIT: Cold ischaemic time; DGF: Delayed graft function; PGF: Primary graft function; DBD: Brain death; DCD: Circulatory death.

Table 2 Independent risk factors for delayed graft function

Variable	OR	95%CI	P value
Black Ethnicity	2.27	1.28-4.00	0.0047
Female gender	0.43	0.25-0.73	0.0017
DCD donor	4.09	2.33-7.20	< 0.0001
Preformed DSA	2.36	1.07-5.18	0.0326
CIT	1.05	1.02-1.08	0.0009
Donor age	1.02	1.01-1.04	0.0049
Time on dialysis	1.07	1.02-1.11	0.0023

CIT: Cold ischaemic time; DCD: Circulatory death.