Current techniques for AB0-incompatible living donor liver transplantation

Table 1 Research regarding AB0-incompatible living donor liver transplantation published since 2010

Ref.	Pat No.	Splenectomy local graft infusion	Rituximab	IVIG	PTP Target iso-titer	IS	AMR
Lee et al[59]	15	-/-	-14 d 300 mg/m2	+1, +4 d 0.8 g/kg bw	First -7 d 1:8	Triple	No
Shen et al[31]	35	n.s.	Z 375 mg/m2	Z 0.4 g/kg bw	Rescue	Quadruple	2
Lee et et al[59]	15	-/-	-14 d, 300 mg/m2 Z, +4 d, 200 mg/m2	No	TPE < 1:8	Triple	No
Kim et al[36]	14	-/-	-7 d 375 mg/m2	+1, +3, +5 d 0.6 g/kg bw	TPE 1:32	-3 d MMF 1.5 g triple	No
Song et al[52]	10	-/+	-14 d, 375 mg/m2	No	TPE 1:32	Triple with Cyc	No
Kim et al[20]	22	-/-	-14 d, 375 mg/m2	No	PP 1:32	PGE1 Triple	No
Lee et al[34]	20	-/-	-15 d 300 mg/m2	+1, +4 d 0.8 g/kg bw	TPE < 1.16	Quadruple	No
Song et al[66]	20	-/+	-21, -14 d 300, 375 mg/m2	No	TPE 1:8	Triple with Cyc	No
Song et al[66]	21-127	-/-	-21, -14 d 300, 375 mg/m2	No	TPE 1:8	Triple	No
Song et al[66]	128-235	+/-	-21, -14 d 300, 375 mg/m2	No	TPE 1:8	Triple	17
Yasuda et al[67]	5	+/-	-15, -3 d 500 mg/m2	No	TPE n.s.	Triple	4
Lee et al[35]	19	-/-	-10 d 300-375 mg/m2	No	TPE 1:32	-7 d Tac 0.1 mg/kg, quadruple	No
Lee et al[68] (Initial iso-titer < 1:64)	20	-/-	+1 d, 375 mg/m2	No	< 1:64	Quadruple	No
Lee et al[68] (Initial iso-titer > 1:64)	26	-/-	-21 d, 375 mg/m2 +1 d, 187 mg/m2	No	TPE/PP < 1:64	Quadruple	No

Quadruple: Tacrolimus, mycophenolate mofetil, basiliximab, steroids; Triple: Tacrolimus, mycophenolate mofetil, steroids; TPE: Therapeutic plasma exchange; IS: Immunosuppression: 5 d before transplantation - -5 d, 5 d after TX - +5 d, day of TX - Z; Cyc: Cyclophosphamide; PP: Plasmapheresis, not otherwise specified; PGE1: Prostaglandin E1, gabexate mesilate; Tac: Tacrolimus.