Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Transplant. Dec 24, 2014; 4(4): 216-221
Published online Dec 24, 2014. doi: 10.5500/wjt.v4.i4.216
Table 1 Epidemiologic features differentiating type 1 from type 2 diabetes mellitus
CharacteristicType 1 DMType 2 DM
Age (yr, at diagnosis)< 25> 25
OnsetAbruptGradual
Body HabitusLean (weight < 105% of IBW)Overweight/Obese (weight > 115% of IBW)
HLA-associationYesNo
C-peptideUndetectableDetectable
KetoacidosisYesNo
Immediate need for insulinYesNo
Table 2 Proposed simultaneous pancreas-kidney type 2 diabetic selection criteria
Age < 55 yr
BMI < 30 kg/m2
Insulin dependence
Total insulin requirements < 1 U/kg of IBW/d
Presence of renal failure (dialysis dependent or pre-dialysis advanced diabetic nephropathy with GFR ≤ 20 mL/min per 1.73 m2
Fasting c-peptide < 10 ng/mL
Low cardiac and vascular disease risk
History of medical and dietary compliance