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©The Author(s) 2025.
World J Transplant. Mar 18, 2025; 15(1): 98975
Published online Mar 18, 2025. doi: 10.5500/wjt.v15.i1.98975
Published online Mar 18, 2025. doi: 10.5500/wjt.v15.i1.98975
Table 1 Patients’ characteristics at intensive care unit admission, n (%)/median (25th-75th percentiles)
| Total population (n = 91) | SOT (n = 28) | HSCT (n = 63) | χ² | P value | |
| Age at admission (years) | 56 (43.2-64.7) | 61 (51.5-68) | 54 (40.5-61) | NA | < 0.01 |
| Age at transplantation (years) | 50 (36.2-59) | 50 (36.7-58.2) | 51 (35-60) | NA | 0.86 |
| Male gender | 55 (60.4) | 17 (60.7) | 38 (60.3) | 0.001 | 0.97 |
| Comorbidities | |||||
| Cardiovascular | 56 (61.5) | 26 (92.9) | 30 (47.6) | 16.76 | < 0.01 |
| Respiratory | 13 (14.3) | 3 (10.7) | 10 (15.9) | NA | 0.51 |
| Chronic kidney disease | 34 (37.4) | 26 (92.9) | 8 (12.7) | 53.22 | < 0.01 |
| Chronic hemodialysis | 11 (12.1) | 9 (32.1) | 2 (3.2) | NA | < 0.01 |
| Diabetes | 16 (17.6) | 7 (25) | 9 (14.3) | 1.53 | 0.21 |
| Malignant disease | 11 (12.1) | 4 (14.3) | 7 (11.1) | NA | 0.70 |
| Disease severity | |||||
| SOFA | 9 (6-11) | 7.5 (5-11) | 9 (7-10) | NA | 0.37 |
| APACHE II | 22 (17.5-27) | 19 (14-22) | 23 (19-27) | NA | 0.01 |
| Respiratory support | 48 (52.7) | 12 (42.9) | 36 (57.1) | 1.58 | 0.20 |
| Vasoactive medication support | 32 (35.2) | 9 (32.1) | 23 (36.5) | 0.16 | 0.68 |
Table 2 Organ support during intensive care unit stay and outcome, n (%)/median (25th-75th percentiles)
| Total population (n = 91) | SOT (n = 28) | HSCT (n = 63) | |
| Mechanical ventilation | 73 (80.2) | 18 (64.3) | 55 (87.3)a |
| Vasoactive medication support | 65 (71.4) | 13 (46.4) | 52 (82.5)a |
| Acute renal replacement therapy | 51 (56) | 21 (75) | 30 (47.6)a |
| ICU survival | 24 (26.4) | 16 (57.1) | 8 (12.7)a |
| 7 days survival | 49 (53.8) | 22 (78.6) | 27 (42.9)a |
| 28 days survival | 36 (39.6) | 21 (75) | 15 (23.8)a |
| 60 days survival | 27 (29.7) | 18 (64) | 9 (14.3)a |
| ICU LOS | 7 (3-17) | 9.5 (3-26) | 7 (3.2-16) |
| Hospital LOS | 28 (12-48.7) | 35.5 (17.2-48.7) | 22 (11.2-48.7) |
Table 3 Comparison of patients with and without sepsis, n (%)/median (25th-75th percentiles)
| Sepsis/ septic shock (n = 53) | Other diagnoses (n = 38) | |
| Age at admission | 55 (43.5-63.2) | 57 (46-65) |
| Age at transplantation | 50 (36.7-58.2) | 54 (41-59) |
| Male gender | 30 (56.6) | 25 (65.8) |
| Comorbidites | ||
| Cardiovascular | 32 (60.4) | 24 (63.2) |
| Respiratory | 5 (9.4) | 8 (21.1) |
| Chronic kidney disease | 18 (34.0) | 16 (42.1)a |
| Chronic hemodialysis | 4 (7.5) | 7 (18.4) |
| Diabetes | 10 (18.9) | 6 (15.8) |
| Malignant disease | 7 (13.2) | 4 (10.5) |
| Respiratory support at admission | 27 (50.9) | 21 (55.3) |
| Vasoactive medication support at admission | 26 (49.1) | 6 (15.8)a |
| APACHE II | 24.5 (19-28) | 19.5 (15.5-23)a |
| SOFA | 9 (7-12.5) | 8 (5-9)a |
| Acute renal replacement therapy | 35 (66.0) | 16 (42.1)a |
| Mechanical ventilation | 47 (88.7) | 26 (68.4)a |
| Vasoactive medication support | 47 (88.7) | 18 (47.4)a |
| ICU LOS | 8 (4-17) | 5 (2-16) |
| Hospital LOS | 30 (14.5-52.5) | 19 (11-45) |
| ICU survival | 8 (15.1) | 16 (42.1)a |
| 7 days survival | 22 (41.5) | 27 (71.1)a |
| 28 days survival | 15 (28.3) | 21 (55.3)a |
| 60 days survival | 10 (18.9) | 17 (44.7)a |
- Citation: Vujaklija Brajkovic A, Kosuta I, Batur L, Sundalic S, Medic M, Vujevic A, Bielen L, Babel J. Patients admitted in the intensive care unit after solid organ or bone marrow transplantation: Retrospective cohort study. World J Transplant 2025; 15(1): 98975
- URL: https://www.wjgnet.com/2220-3230/full/v15/i1/98975.htm
- DOI: https://dx.doi.org/10.5500/wjt.v15.i1.98975