Haemodynamic management in brain death donors: Influence of aetiology of brain death

doi:10.5500/wjt.v13.i4.183

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 13, Issue 4

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (1507)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-2) series.

Item

Count

PDF

WORD

HTML

791

Tables (1-2)

215

Sum=1107

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

100

Download

217

Sum=317

Jun 18, 2023 (publication date) through May 11, 2024

Times Cited of This Article

Times Cited (1)

Journal Information of This Article

Publication Name

World Journal of Transplantation

ISSN

2220-3230

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Transplant. Jun 18, 2023; 13(4): 183-189
Published online Jun 18, 2023. doi: 10.5500/wjt.v13.i4.183

Table 1 Study population, n (%)

	Stroke	Traumatic brain injury	Postanoxic encelophaphy
Number	71	48	19
Age (yr, mean ± SD)	79 ± 14	68 ± 20	59 ± 19	0.0007^a
Males	34 (48)	31 (65)	10 (53)	0.197^b
Risk factors				0.673^b
Hypertension	51	10	24
Diabetes	24	9	16
Heart disease	6	2	5
Refusals to donation	13	10	2	0.613^b
Utilized donors (n)	54	35	15	0.808^b
Utilization rate (%)	93	92	89

^aOne way analysis of variance.

^bχ².

Table 2 Haemodynamic data, n (%)

	Stroke	Traumatic brain injury	Postanoxic encephalopathy
Number	71 (51)	48 (35)	19 (14)
ICU admission
SBP (mmHg), mean ± SD	112 ± 44	123 ± 34	98 ± 33	0.002^a
DBP (mmHg), mean ± SD	74 ± 21	74 ± 18	77 ± 22	0.001^a
HR (bpm), mean ± SD	75 ± 22	77 ± 34	82 ± 35	0.015^a
CVP (cmH₂O), mean ± SD	10 ± 3	11 ± 4	10 ± 3	0.819^a
Norepinephrine	31 (44)	29 (60)	14 (74)	0.03^b
Other vasoactive drugs	5 (7)	9 (18)	6 (32)	0.015^b
Urine output, median (IQR)	200 (125-393)	261 (124-408)	287 (186-440)	0.279^a
Lactate (mg/dL), median (IQR)	1.5 (1-2.6)	2.1 (1.3-3.1)	1.8 (0.8-4.6)	0.033^a
Time 1
SBP (mmHg), mean ± SD	123 ± 19	125 ± 23	122 ± 21	0.818^a
DBP (mmHg), mean ± SD	63 ± 13	65 ± 14	68 ± 17	0.497^a
HR (bpm), mean ± SD	86 ± 16	92 ± 17	94 ± 22	0.037^a
Norepinephrine	56 (78)	43 (89)	18 (95)	0.120^b
CVP (cmH₂O), mean ± SD	10 ± 3	11 ± 5	12 ± 7	0.001^a
Other vasoactive drugs	7 (9.8)	10 (20)	5 (26)	0.113^b
Urine output, median (IQR)	113 (57-210)	115 (85-285)	110 (65 220)	0.374^a
Lactate (mg/dL), median (IQR)	1.2 (0.9-1.7)	1.4 (1-3.1)	1.7 (1.3-3.1)	0.006^a
Time 2
SBP (mmHg), mean ± SD	133 ± 25	131 ± 22	126 ± 27	0.510^a
DBP (mmHg), mean ± SD	66 ± 14	65 ± 12	70 ± 17	0.784^a
HR (bpm), mean ± SD	94 ± 19	95 ± 15	99 ± 25	0.760^a
Norepinephrine	57	43	18	0.172^b
Other vasoactive drugs	8 (11)	6 (12)	5 (26)	0.227^b
CVP (cmH₂O), mean ± SD	10 ± 4	12 ± 4 (12)	13 ± 4	0.040^a
Urine output, median (IQR)	143 (79-240)	160 (95-250)	200 (92-250)	0.785^a

^aOne-way analysis of variance.

^bχ².

IQR: Interquartile range; ICU: Intensive care unit; CVP: Central venous pressure, SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HR: Heart rate.

Citation: Lazzeri C, Bonizzoli M, Batacchi S, Guetti C, Vessella W, Valletta A, Ottaviano A, Peris A. Haemodynamic management in brain death donors: Influence of aetiology of brain death. World J Transplant 2023; 13(4): 183-189
URL: https://www.wjgnet.com/2220-3230/full/v13/i4/183.htm
DOI: https://dx.doi.org/10.5500/wjt.v13.i4.183