Factors affecting complications development and mortality after single lung transplant

Table 1 Primary graft dysfunction classification

PGD grade	Chest radiography		PaO2/FiO2 ratio in mmHg	SaO2/FiO2 ratio
	Diffuse allograft infiltration	Pulmonary edema
0	No	No	Any	Any
1	Yes	Yes	> 300	> 315
2	Yes	Yes	200-300	235-315
3	Yes	Yes	< 200	< 235

FiO₂: Fraction of inspired oxygen; PaO₂: Partial oxygen pressure; PGD: Primary graft dysfunction; SaO₂: Oxygen saturation.

Table 2 Possible risk factor associated with the development of primary graft dysfunction

Risk factor for PGD
Factors correlated with the recipient	Factors correlated with the donor	Other (Intra- and post-operative)
BMI ≥ 25	Heavy smoker	Intracellular type preservation solutions
Sarcoidosis	DCD	Prolonged warm or/and cold ischemia
IPF	Traumatic brain injury/DBD	SLT
PPH	Female gender	Poly-transfusion of blood product
Elevated mean PAP	African American ethnicity	Use of cardiopulmonary bypass
LVDD	Younger than 21 yr, older than 45	High fractional inspired oxygen upon reperfusion
	Alcoholism	Prolonged mechanical ventilation
	Aspiration	Peri-operative insults

BMI: Body mass index; DBD: Donation after brain death; DCD: Donation after circulatory death; IPF: Idiopathic pulmonary fibrosis; LVDD: Left ventricular diastolic dysfunction; PGD: Primary graft dysfunction; PPH: Primary pulmonary hypertension; SLT: Single lung transplant.