Review
Copyright ©The Author(s) 2020.
World J Transplant. Jul 29, 2020; 10(7): 183-190
Published online Jul 29, 2020. doi: 10.5500/wjt.v10.i7.183
Table 1 Risk of cytomegalovirus infection based on donor and recipient serostatus
DonorRecipientRiskRecommended prophylaxis length
PositiveNegativeHighest6 months
PositivePositiveHigher3 months
NegativePositiveModerate3 months
NegativeNegativeLowNot recommended
Table 2 Antiviral drugs for cytomegalovirus prophylaxis and treatment in liver transplant patients
DrugRouteProphylaxis doseTreatment doseSide effects
GanciclovirIV5 mg/kg daily5 mg/kg twice a dayBone marrow suppression
ValganciclovirOral900 mg once a day900 mg twice a dayLeukopenia
FoscarnetIV-60 mg/kg every 8 h or 90 mg/kg every 12 hNephrotoxicity
CidofovirIV-5 mg/kg weekly × 2, then every 2 wkNephrotoxicity