Long term outcomes of cardiac transplant for immunoglobulin light chain amyloidosis: The Mayo Clinic experience

Figure 1 Overall survival. A: Overall survival from orthotopic heart transplant; B: Overall survival comparing OHT for AL amyloidosis to OHT from 1992 to 2011 for non-amyloid indications; C: Comparison of survival with non OHT subgroups. OHT: Orthotopic heart transplantation; CHF: Congestive heart failure; AL: Immunoglobulin light chain.

Figure 2 Influence of chemotherapy on overall survival. A: Overall survival (OS) based on hematologic response. The median OS for the 11 non-responders/non-evaluable patients was 1.2 years. The median OS for the 5 patients achieved VGPR or PR was 5.4 years. The median OS for the 7 patients achieving CR was 10.8 years; B: OS based on whether or not patient received AHSCT. The median OS for the 10 patients not undergoing AHSCT was 2.4 years; the median OS For the 13 patients undergoing AHSCT was 6.3 years. VGPR: Very good partial response; CR: Complete hematologic response; AHSCT: Autologous hematopoietic stem cell transplantation.