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World J Transplant. Dec 18, 2024; 14(4): 96687
Published online Dec 18, 2024. doi: 10.5500/wjt.v14.i4.96687
Ethical frontiers in liver transplantation
Hoi Pong Nicholas Wong, Surya Varma Selvakumar, Pei Yi Loh, Jovan Yi Jun Liau, Matthias Yi Quan Liau, Vishalkumar Girishchandra Shelat
Hoi Pong Nicholas Wong, Surya Varma Selvakumar, Pei Yi Loh, Jovan Yi Jun Liau, Matthias Yi Quan Liau, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore
Vishalkumar Girishchandra Shelat, Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore
Vishalkumar Girishchandra Shelat, Surgical Science Training Centre, Tan Tock Seng Hospital, Singapore 308433, Singapore
Author contributions: Wong HPN, Liau MYQ, and Shelat VG contributed to conceptualization, methodology; Wong HPN, Liau MYQ, Shelat VG, Selvakumar SV, Loh PY, and Liau JYJ contributed to investigation, writing; Shelat MYVG contributed to supervision.
Conflict-of-interest statement: All authors declare that there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Vishalkumar Girishchandra Shelat, FEBS, FRCS, MBBS, MMed, Adjunct Associate Professor, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore. vgshelat@gmail.com
Received: May 13, 2024
Revised: August 26, 2024
Accepted: September 10, 2024
Published online: December 18, 2024
Processing time: 130 Days and 0.5 Hours
Core Tip

Core Tip: Liver transplantation stands as a beacon of hope for individuals battling end-stage liver disease, offering the promise of extended life and improved quality of life. However, behind the lifesaving potential of this procedure lies intricate ethical considerations that demand careful examination. In this article, we delve into the multifaceted ethical issues surrounding liver transplantation, exploring the allocation of scarce resources, the challenges of organ procurement and distribution, transplant tourism, and the implications of emerging technologies. As the use of artificial intelligence grows, we also explore its potential role in liver transplantation as well as the ethical issues that accompany it.