Observational Study
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World J Transplant. May 18, 2022; 12(5): 100-111
Published online May 18, 2022. doi: 10.5500/wjt.v12.i5.100
Simultaneous nephrectomy during kidney transplantation for polycystic kidney disease does not detrimentally impact comorbidity and graft survival
Tom Darius, Sébastien Bertoni, Martine De Meyer, Antoine Buemi, Arnaud Devresse, Nada Kanaan, Eric Goffin, Michel Mourad
Tom Darius, Sébastien Bertoni, Martine De Meyer, Antoine Buemi, Michel Mourad, Surgical and Abdominal Transplantation Unit, University Clinics Saint Luc, Brussels 1200, Belgium
Arnaud Devresse, Nada Kanaan, Eric Goffin, Division of Nephrology, University Clinics Saint Luc, Brussels 1200, Belgium
Author contributions: Darius T and De Meyer M designed the research; Bertoni S, De Meyer M and Darius T performed the research; Darius T analyzed the data; Darius T wrote the paper.
Institutional review board statement: This study was approved by the Institutional Board of our University Hospital on July 6, 2020.
Informed consent statement: All study participants provided informed written consent regarding personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
Data sharing statement: The original anonymous dataset is available on request from the corresponding author at tom.darius@uclouvain.be
STROBE statement: The manuscript was prepared according to the STROBE statement - checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tom Darius, FRCS (Gen Surg), MD, PhD, Doctor, Professor, Surgeon, Surgical and Abdominal Transplantation Unit, University Clinics Saint Luc, Avenue Hippocrate 10, Brussels 1200, Belgium. tom.darius@uclouvain.be
Received: March 31, 2021
Peer-review started: March 31, 2021
First decision: July 29, 2021
Revised: August 11, 2021
Accepted: April 9, 2022
Article in press: April 9, 2022
Published online: May 18, 2022
Core Tip

Core Tip: The associated surgical comorbidity and graft survival of an ipsilateral nephrectomy during isolated kidney transplantation in patients with autosomal dominant polycystic kidney disease was evaluated. One hundred and fifty-four patients were retrospectively evaluated, of which 77 did and 77 did not undergo associated ipsilateral nephrectomy during the transplantation. In a long-term follow-up, we observed no negative impact on surgical comorbidity and graft survival of a simultaneous ipsilateral native nephrectomy to create space for graft positioning during kidney transplantation in patients with autosomal dominant polycystic kidney disease.