Systematic Reviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Nov 18, 2021; 11(11): 480-502
Published online Nov 18, 2021. doi: 10.5500/wjt.v11.i11.480
Native and transplant kidney histopathological manifestations in association with COVID-19 infection: A systematic review
Vishnu Jeyalan, Joshua Storrar, Henry H L Wu, Arvind Ponnusamy, Smeeta Sinha, Philip A Kalra, Rajkumar Chinnadurai
Vishnu Jeyalan, Henry H L Wu, Arvind Ponnusamy, Department of Renal Medicine, Royal Preston Hospital, Preston PR2 9HT, United Kingdom
Joshua Storrar, Smeeta Sinha, Philip A Kalra, Rajkumar Chinnadurai, Department of Renal Medicine, Salford Care Organisation, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, United Kingdom
Joshua Storrar, Smeeta Sinha, Philip A Kalra, Rajkumar Chinnadurai, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, United Kingdom
Author contributions: Jeyalan V, Storrar J, Wu HHL, and Chinnadurai R performed the conception/design of the study, acquisition, analysis and interpretation of data, manuscript drafting, critical revision, final approval; Ponnusamy A performed the conception/design of the study, critical revision, final approval; Sinha S, and Kalra PA performed the critical revision, final approval.
Conflict-of-interest statement: The authors have no conflict of interest and no financial ties to declare.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rajkumar Chinnadurai, MRCP, PhD, Consultant Physician-Scientist, Department of Renal Medicine, Salford Care Organisation, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford M6 8HD, United Kingdom. rajkumar.chinnadurai@srft.nhs.uk
Received: March 31, 2021
Peer-review started: March 31, 2021
First decision: July 29, 2021
Revised: August 5, 2021
Accepted: October 31, 2021
Article in press: October 31, 2021
Published online: November 18, 2021
Processing time: 225 Days and 7.3 Hours
Core Tip

Core Tip: Coronavirus disease 2019 (COVID-19) affects multiple organ systems, including the kidneys resulting in acute kidney injury. Multiple pathologies and different mechanisms have been attributed to the pathogenesis of kidney disease in COVID-19. This systematic review aims to provide an overview of the histopathological findings reported in kidney biopsies associated with COVID-19 infection.