Synovial mesenchymal stem cells in vivo: Potential key players for joint regeneration

doi:10.5499/wjr.v1.i1.4

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Dec 31, 2011 (publication date) through Jan 8, 2025

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World Journal of Rheumatology

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2220-3214

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Rheumatol. Dec 31, 2011; 1(1): 4-11
Published online Dec 31, 2011. doi: 10.5499/wjr.v1.i1.4

Table 1 Synovial mesenchymal stem cell isolation studies based on pre-defined phenotypes

Candidate phenotype	Control standard culture:“without separation”		Control negative fraction:“opposite phenotype”
	Expansion capacity	Differentiation capacity	Expansion capacity	Differentiation capacity
CD9⁺CD90⁺ CD166^+[14]	NR	Similar	NR	NR
SP (bovine)[98]	NR	NR	NR	Chondro: similar
SP (bovine)[99]	NR	NR	Significantly lower	Chondro: inferior Osteo: similar Myo: absent
CD105^+[100]	NR	Chondro:present	NR	Chondro:present
CD45^-CD31^-[18]	NR	NR	Absent	NR

First described for muscle and hemopoietic stem cells[101,102]. Chondro: Chondrogenesis; Osteo: Osteogenesis; Myo: Myogenesis; NR: Not reported; SP: Side population, this cell population is defined functionally and cytometrically by the ability of cells to expel fluorescent dyes.

Citation: Jones E, McGonagle D. Synovial mesenchymal stem cells in vivo: Potential key players for joint regeneration. World J Rheumatol 2011; 1(1): 4-11
URL: https://www.wjgnet.com/2220-3214/full/v1/i1/4.htm
DOI: https://dx.doi.org/10.5499/wjr.v1.i1.4