Nomogram for predicting the risk of anxiety and depression in patients with non-mild burns

Table 1 Patient characteristics in the development and validation sets, n (%)

Characteristic	Development set (n = 450)	Validation set (n = 225)	P value
Sex			0.386
Male	305 (67.8)	145 (64.4)
Female	145 (32.2)	80 (35.6)
Age (years)			0.782
< 33	265 (58.9)	135 (60)
≥ 33	185 (41.1)	90 (40)
Personal status			0.174
Married	215 (47.8)	120 (53.3)
Unmarried	235 (52.2)	105 (46.7)
Income			0.582
Satisfied	190 (42.2)	100 (44.4)
Unsatisfied	260 (57.8)	125 (55.6)
Education			0.368
Middle school or lower	125 (27.8)	70 (31.1)
Higher than middle school	325 (72.2)	155 (68.9)
Medical settlement			0.740
Self-funded	95 (21.1)	50 (22.2)
Medical insurance	355 (78.9)	175 (77.8)
Burn area			0.780
11%-29%	275 (61.1)	135 (60)
≥ 30%	175 (38.9)	90 (40)
Causes of burns			0.831
Flame burn	220 (48.9)	115 (51.1)
Hot liquid burn	185 (41.1)	85 (37.8)
Electric burn	20 (4.4)	10 (4.4)
Other	25 (5.6)	15 (6.7)
Burn site			0.913
Head, face, and neck area	240 (53.3)	119 (52.9)
Limbs and trunk area	210 (46.7)	106 (47.1)
Hospitalization period			0.130
< 14	135 (30)	55 (24.4)
≥ 14	315 (70)	170 (75.6)
Anxiety rate	210 (46.7)	90 (40)	0.100
Depression rate	175 (38.9)	95 (42.2)	0.405

Table 2 Logistic regression analysis of anxiety-related factors

Characteristic	Univariate analysis		Multivariate analysis
	Odds ratio (95%CI)	P value	Odds ratio (95%CI)	P value
Sex
Male	Reference		Reference
Female	2.846 (1.515-3.504)	0.008	1.149 (1.013-1.241)	0.013
Age (years)
≥ 33	Reference		Reference
< 33	3.955 (1.275-5.269)	0.017	3.905 (2.588-5.296)	0.008
Personal status
Married	Reference		Reference
Unmarried	1.290 (1.094-1.893)	0.031	1.109 (1.014-1.870)	0.036
Burn area
11%-29%	Reference		Reference
≥ 30%	2.500 (1.431-3.150)	0.010	2.006 (1.638-2.399)	0.005
Burn site
Limbs and trunk area	Reference		Reference
Head, face, and neck area	2.926 (2.011-3.853)	0.002	3.571 (2.531-4.301)	0.008
Income
Satisfied	Reference
Unsatisfied	0.904 (0.308-2.656)	0.855
Education
Middle school or lower	Reference
Higher than middle school	0.796 (0.254-2.491)	0.695
Medical settlement
Self-funded	Reference
Medical insurance	0.871 (0.248-3.055)	0.829
Causes of burns
Flame burn	Reference
Hot liquid burn	1.067 (0.339-3.354)	0.912
Electric burn	0.667 (0.061-7.254)	0.739
Other	1.000 (0.081-12.399)	1.000
Hospitalization period (days)
< 14	Reference
≥ 14	0.818 (0.279-2.402)	0.715

The data derived from the development set.

Table 3 Logistic regression analysis of depression-related factors

Characteristic	Univariate analysis		Multivariate analysis
	Odds ratio (95%CI)	P value	Odds ratio (95%CI)	P value
Sex
Male	Reference		Reference
Female	1.615 (1.278-2.499)	0.005	1.801 (1.132-2.229)	0.035
Age (years)
≥ 33	Reference		Reference
< 33	1.372 (1.164-1.769)	0.025	1.483 (1.280-1.987)	0.006
Personal status
Married	Reference		Reference
Unmarried	1.294 (1.003-1.843)	0.023	1.123 (1.020-1.740)	0.022
Burn area
11%-29%	Reference		Reference
≥ 30%	1.562 (1.165-1.896)	< 0.001	1.986 (1.537-2.254)	< 0.001
Burn site
Limbs and trunk area	Reference		Reference
Head, face, and neck area	2.667 (1.224-3.980)	0.020	2.199 (1.399-3.486)	0.021
Income
Satisfied	Reference
Unsatisfied	0.887 (0.557-0.997)	0.578
Education
Middle school or lower	Reference
Higher than middle school	0.579 (0.354-1.457)	0.897
Medical settlement
Self-funded	Reference
Medical insurance	0.457 (0.257-1.789)	0.456
Causes of burns
Flame burn	Reference
Hot liquid burn	1.026 (0.789-1.456)	0.789
Electric burn	0.746 (0.554-1.254)	0.678
Other	1.000 (0.045-11.245)	1.000
Hospitalization period (days)
< 14	Reference
≥ 14	0.667 (0.421-0.843)	0.347

The analysis used data from the development set.