Therapeutic effect and psychological impact of aspirin plus edaravone on patients with cerebral infarction

Table 1 General data, n (%)

Factors	Observation group (n = 65)	Control group (n = 59)	χ2	P value
Sex			0.002	0.065
Male	35 (53.85)	32 (54.24)
Female	30 (46.15)	27 (45.76)
Age (yr)			0.026	0.871
≤ 65	31 (47.69)	29 (49.15)
> 65	34 (52.31)	30 (50.85)
BMI (kg/m2)			0.039	0.844
≤ 23	32 (49.23)	28 (47.46)
> 23	33 (50.77)	31 (52.54)
History of smoking			0.009	0.923
Yes	38 (58.46)	35 (59.32)
No	27 (41.54)	24 (40.68)
Diabetes			0.009	0.993
Yes	32 (49.23)	29 (49.15)
No	33 (50.77)	30 (50.85)
Hypertension			0.084	0.772
Yes	38 (58.46)	36 (61.02)
No	27 (41.54)	23 (38.98)
Drinking habit			0.001	0.981
Yes	42 (64.62)	38 (64.41)
No	23 (35.38)	21 (35.59)

BMI: Body mass index.

Table 2 Comparison of therapeutic efficacy, n (%)

Curative effect	Observation group (n = 65)	Control group (n = 59)	χ2	P value
Markedly effective	38 (58.46)	25 (42.37)	-	-
Effective	24 (36.92)	21 (35.59)	-	-
Ineffective	3 (4.62)	13 (22.03)	-	-
Effectiveness of treatment	62 (95.38)	46 (77.97)	8.350	0.004

Table 3 Comparison of neurological deficit scores

Time	Observation group (n = 65)	Control group (n = 59)	t	P value
Before treatment	22.18 ± 1.01	22.24 ± 1.13	0.312	0.755
After treatment	11.25 ± 1.05	17.00 ± 1.10	29.772	< 0.001

Table 4 Comparison of daily living ability

Time	Observation group (n = 65)	Control group (n = 59)	t	P value
Before treatment	52.34 ± 1.53	52.42 ± 1.80	0.267	0.790
After treatment	67.20 ± 1.54	59.37 ± 1.68	27.079	< 0.001

Table 5 Comparison of cognitive function

Time	Observation group (n = 65)	Control group (n = 59)	t	P value
Before treatment	21.06 ± 1.07	21.15 ± 1.22	0.438	0.663
After treatment	24.94 ± 1.09	23.20 ± 1.00	9.232	< 0.001

Table 6 Comparison of adverse reactions during medication, n (%)

Adverse reactions	Observation group (n = 65)	Control group (n = 59)	χ2	P value
Skin ecchymosis	2 (3.08)	1 (1.69)	-	-
Black stool	2 (3.08)	2 (3.39)	-	-
Dizziness	3 (4.62)	1 (1.69)	-	-
Stomach bleeding	2 (3.08)	1 (1.69)	-	-
Total incidence	9 (13.85)	5 (8.47)	0.891	0.345

Table 7 Comparison of the quality of life after treatment

Quality of life	Observation group (n = 65)	Control group (n = 59)	t	P value
Body function	62.28 ± 1.39	49.49 ± 1.60	47.625	< 0.001
Social function	65.09 ± 1.44	51.07 ± 1.57	51.868	< 0.001
Physiological state	63.25 ± 1.35	52.00 ± 1.13	50.041	< 0.001
Mental state	65.09 ± 1.38	53.19 ± 1.33	48.788	< 0.001