Copyright
©The Author(s) 2024.
World J Psychiatry. May 19, 2024; 14(5): 607-623
Published online May 19, 2024. doi: 10.5498/wjp.v14.i5.607
Published online May 19, 2024. doi: 10.5498/wjp.v14.i5.607
Ref. | Herbs | Herbal constituents | Administration dosage | Models | Mechanism of action |
Terpenes and phenylpropanoids | |||||
Alotaibi et al[78], 2022 | Illicium dunnianum Tutch. | Macranthol | 10, 20, 40 mg/kg, p.o. | CUMS mice | BDNF |
Dai et al[56], 2022 | Magnolia officinalis Rehd et Wils. | Honokiol | 2, 4, 8 mg/kg, i.g. | CUMS mice | The HPA axis/BDNF |
Zhao et al[40], 2023 | Psoralea corylifolia Linn. | Bakuchiol analogs | 0.03-333 μM | Tr-CHO cells | Monoamine |
Zeng et al[79], 2021 | Hemsleya amabilis Diels | Cucurbitacin IIa | 2.5, 5 mg/kg, i.p | CUMS mice | BDNF |
Chen et al[80], 2023 | Crocus sativus L. | Crocin | 12.5, 25, 50 mg/kg, i.p. | Rats | BDNF |
Adam et al[116], 2023 | Perilla frutescens (L.) Britt. | Rosmarinic acid | 5 and 10 mg/kg, i.p. | CUS Rats | BDNF |
Carbohydrates | |||||
Bildziukevich et al[117], 2023 | Acanthopanax Miq. | Chiisanoside | 2.5 and 5 mg/kg, i.p | LPS-induced mice | BDNF |
Salehi et al[118], 2023 | Aconitum carmichaelii Debeaux | Fuzi polysaccharide 1 | 50, 100 mg/kg, i.p. | Mice | BDNF |
Li et al[119], 2022 | Morinda officinalis How | Oligosaccharide | 5, 10, 125, 500 mM | CORT-induced PC12 | The HPA axis |
Alkaloids | |||||
Salehi et al[118], 2023 | Aconitum carmichaelii Debeaux | Total alkaloid | 10, 30 mg/kg, i.g. | Ovariectomized mice | BDNF |
Ali et al[120], 2023 | Stephania tetrandra S. Moore | Tetrandrine | 10, 20, 40 mg/kg, i.g. | CUMS Rats | Monoamine/BDNF |
Shayganfard[121], 2023 | Berberis aristata Linn. | Berberine Chloride | 5, 10, 20 mg/kg, i.p | Male albino mice | Monoamine |
Sun et al[122], 2023 | Scutellaria baicalensis Georgi | Baicalein | 1, 2, 4 mg/kg, i.p. | CUMS mice | BDNF |
Flavonoids | |||||
Yu et al[123], 2022 | Pueraria lobate (Willd.) Ohwi | Puerarin | 60 and 120 mg/kg, i.g | CUS Rats | Monoamine/the HPA axis |
Yu et al[123], 2022 | Pueraria lobate (Willd.) Ohwi | Pueraria isoflavone | 10 and 100 mg/kg | Ovariectomy mice | BDNF |
Wang et al[124], 2021 | Apocynum venetum L. | Flavonoid Extract | 25, 50, 100 mg/ml | CORT-induced PC12 | BDNF |
Mu and Ma[125], 2022 | Gastrodia elata Bl. | Gastrodin | 50, 100, 200 mg/kg, i.p. | CUS Rats | BDNF |
Glycosides | |||||
Nagakura[126], 2022 | Gentiana lutea L. | Gentiopicroside | 50, 100, 200 mg/kg, i.g. | Reserpine-induced mice | Glutamate transmission |
Yin et al[127], 2023 | Paeonia lactiflora Pall. | Total glycosides | 160 mg/kg, p.o. | CORT-induced rats | BDNF |
Sánchez et al[128], 2023 | Rhodiola rosea L. | Salidroside | 20, 40 mg/kg, p.o | Behavioral despair rats | The HPA axis/BDNF |
Saponins | |||||
Liu et al[129], 2023 | Anemarrhena asphodeloides Bunge | YY-23 | 20 mg/kg, i.g. | CMS mice | Glutamate transmission |
Zhuang et al[58], 2023 | Bupleurum chinense DC. | Saikosaponin D | 0.75 and 1.50 mg/kg, i.g. | CUMS rats | The HPA axis |
Yoon et al[130], 2023 | Panax ginseng C.A. Mey. | Ginsenoside Rg1 | 40 mg/kg, i.p. | CUMS rats | BDNF |
Tian et al[131], 2023 | Anemarrhena asphodeloides Bunge | Sarsasapogenin | 12.5, 25, 50 mg/kg, p.o. | CUMS mice | Monoamine |
- Citation: Yang Y, Chen YK, Xie MZ. Exploring the transformative impact of traditional Chinese medicine on depression: Insights from animal models. World J Psychiatry 2024; 14(5): 607-623
- URL: https://www.wjgnet.com/2220-3206/full/v14/i5/607.htm
- DOI: https://dx.doi.org/10.5498/wjp.v14.i5.607