Randomized Controlled Trial
Copyright ©The Author(s) 2023.
World J Psychiatry. Aug 19, 2023; 13(8): 583-592
Published online Aug 19, 2023. doi: 10.5498/wjp.v13.i8.583
Table 1 Patient characteristics, n (%)
Variables
Control group (n = 60)
Intervention group (n = 60)
t/χ2
P value
Age (yr)37.95 ± 10.3338.47 ± 10.680.2690.788
Gender2.7190.099
    Male37 (61.67)28 (46.67)
    Female23 (38.33)32 (53.33)
Educational level5.9670.113
Primary school10 (16.67)13 (21.67)
Junior high school40 (66.67)29 (48.33)
Technical secondary school/high school8 (13.33)10 (16.67)
College/undergraduate2 (3.33)8 (13.33)
Medical burden (CNY)3300 ± 27003000 ± 1600-0.8650.389
Annual household income (CNY)45200 ± 3280038500 ± 29200-1.1780.241
Table 2 Family member characteristics, n (%)
Variables
Control group (n = 60)
Intervention group (n = 60)
t/χ2
P value
Age (yr)43.02 ± 10.4442.38 ± 9.40-0.3490.727
Gender                2.3440.126
    Male35 (58.33)43 (71.67)
    Female25 (41.67)17 (28.33)
Educational level                9.2260.026
Primary school3 (5.00)13(21.67)
Junior high school40 (66.67)32 (53.33)
Technical secondary school/high school3 (5.00)6 (10.00)
College/undergraduate14 (23.33)9 (15.00)
Medical burden (CNY)3300 ± 27003000 ± 1600-0.8650.389
Annual household income (CNY)45200 ± 3280038500 ± 29200-1.1780.241
Table 3 Repeated measures analysis of variance on psychopathology, social function, activities of daily living and psychological condition of family members of patients with schizophrenia
Variables
Control group (n = 60), mean ± SD
Intervention group (n = 60), mean ± SD
Repeated measurement, F-test
Before intervention
After intervention
4 wk after intervention
Before intervention
After intervention
4 wk after intervention
Main effect for groups (F, P value, η2partial)
Main effect for time points (F, P value, η2partial)
Group by time point interaction (F, P value, η2partial)
Overall score101.67 ± 21.4875.78 ± 19.3657.90 ± 16.5297.02 ± 24.4068.15 ± 18.8548.72 ± 11.28F = 5.617, P = 0.019, η2partial = 0.045F = 344.924, P = 0.000, η2partial = 0.855F = 0.829, P = 0.439, η2partial = 0.014
Negative factor35.00 ± 5.4226.58 ± 5.8319.77 ± 5.2632.27 ± 7.4824.05 ± 6.3716.45 ± 4.22F = 9.777, P = 0.002, η2partial = 0.077F = 452.858, P = 0.000, η2partial = 0.886F = 0.451, P = 0.638, η2partial = 0.008
Positive factor14.45 ± 3.5010.77 ± 3.018.07 ± 2.5613.70 ± 3.539.60 ± 2.837.40 ± 1.43F = 3.766, P = 0.055, η2partial = 0.031F = 243.801, P = 0.000, η2partial = 0.420F = 0.873, P = 0.420, η2partial = 0.015
Excitatory factor10.53 ± 3.847.45 ± 2.895.85 ± 2.2810.45 ± 3.526.85 ± 2.285.00 ± 1.29F = 1.437, P = 0.233, η2partial = 0.012F = 140.501, P = 0.000, η2partial = 0.451F = 0.801, P = 0.451, η2partial = 0.014
Cognitive factor22.75 ± 4.7217.38 ± 4.3513.45 ± 3.7221.37 ± 5.6115.37 ± 4.2511.23 ± 2.83F = 7.751, P = 0.006, η2partial = 0.062F = 275.171, P = 0.000, η2partial = 0.825F = 0.505, P = 0.605, η2partial = 0.009
Anxiety and depression factor18.82 ± 6.0413.70 ± 5.3611.15 ± 4.3118.45 ± 6.6112.07 ± 4.828.77 ± 3.00F = 3.409, P = 0.067, η2partial = 0.028F = 153.796, P = 0.000, η2partial = 0.724F = 2.130, P = 0.123, η2partial = 0.035
SDSS score12.98 ± 3.5511.1 ± 3.508.72 ± 3.8212.82 ± 3.039.48 ± 3.236.18 ± 3.40F = 5.798, P = 0.018, η2partial = 0.047F = 593.573, P = 0.000, η2partial = 0.910F = 30.062, P = 0.000, η2partial = 0.339
ADL score20.13 ± 8.4916.78 ± 3.9516.25 ± 3.2321.05 ± 8.9416.90 ± 4.0016.23 ± 2.99F = 0.134, P = 0.715, η2partial = 0.001F = 28.065, P = 0.000, η2partial = 0.324F = 0.323, P = 0.724, η2partial = 0.005
Table 4 Medication compliance in the two groups using χ2 test, n (%)
Pre-intervention compliance
Post-intervention compliance
Compliance at 4 wk after intervention
Complete compliance
Partial compliance
Complete compliance
Partial compliance
Complete compliance
Partial compliance
Control group (n = 60)49 (81.67)11 (18.33)48 (80.00)12 (20.00)53 (88.33)7 (11.67)
Intervention group (n = 60)52 (86.67)8 (13.33)50 (83.33)10 (16.67)55 (91.67)5 (8.33)
χ20.5630.2230.370
P value0.4530.6370.543