Research status of internet-delivered cognitive behavioral therapy in cancer patients

Table 1 Research of the internet-delivered cognitive behavioral therapy application in cancer patients

Ref.	Patients (n)	Intervention	Indicators	Conclusion
Nissen et al[18]	Cancer survivors (1282)	Therapist-assisted iMBCT	Outcomes of anxiety and depression	iMBCT is a helpful intervention for cancer survivors suffering from symptoms of anxiety
Zachariae et al[47]	Breast cancer survivors (255)	ICBT-i or waitlist control	Sleep-related outcomes	ICBT-i appears to be effective in breast cancer survivors, with additional benefit in terms of reduced fatigue
Nissen et al[48]	Breast- and prostate cancer survivors (82)	iMBCT	Improvement in anxiety and depression scores from baseline to post-treatment and from baseline to six-months follow-up	iMBCT can be provided for cancer survivors regardless of their age, educational level, and time since diagnosis (up to five years) and therapeutic alliance is not crucial for treatment response
Dirkse et al[49]	Cancer survivors with symptoms of anxiety or depression (86)	ICBT program guided by a technician	Anxiety, depression, fear of cancer recurrence, quality of life	ICBT was associated with improved levels of anxiety, depression, fear of cancer recurrence, and quality of life
Murphy et al[50]	Breast cancer patients with generalized anxiety disorder (14)	ICBT	Health status, adherence, acceptability	ICBT has significant potential to be a suitable modality supervised by clinican
Murphy et al[51]	Cancer survivors (114)	ICBT or TAU	Anxiety and depression symptoms, fear of cancer recurrence, quality of life	Clinician-supervised iCBT has significant benefits for cancer survivors with clinical depression and anxiety disorders
Carbajal-López et al[52]	Gastrointestinal stromal tumors (99)	ICBT or internet-delivered cognitive program	General fatigue, reduced motivation, distress and global health status	Both intervention programs showed reductions in the dimensions of fatigue and improvements in distress and dimensions of quality of life

iMBCT: Internet-delivered mindfulness-based cognitive therapy; TAU: Treat-as-usual; ICBT: Internet-delivered cognitive behavioral therapy.