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©The Author(s) 2021.
World J Psychiatr. Oct 19, 2021; 11(10): 696-710
Published online Oct 19, 2021. doi: 10.5498/wjp.v11.i10.696
Published online Oct 19, 2021. doi: 10.5498/wjp.v11.i10.696
Table 1 Diagnostic criteria for metabolic syndrome
Organization, Year | WHO, 1988 | NCEP/ATP III, 2001 | Modified NCEP/ATP III for Asians, 2004 | IDF, 2006 |
Criteria | Glucose intolerance, IGT, diabetes mellitus, or insulin resistance together with two or more of the following: | Three or more of thefollowing: | Three or more of thefollowing: | Central obesity as defined by ethnicity/race, specific WC, but can be assumed if BMI > 30 kg/m2 and with two or more of the following: |
BP: ≥ 140/90 mmHg | FPG: ≥ 110 mg/dL1 or on treatment for DM | FPG: ≥ 110 mg/dL1 or on treatment for DM | FPG: ≥ 100 mg/dL or on treatment for DM | |
Abdominal obesity: WHR > 0.9 and > 0.85 for men and women, respectively, and/orBMI: > 30 kg/m2 | BP: ≥ 130/85 mmHg | BP: ≥ 130/85 mmHg | BP: ≥ 130/85 mmHg or on treatment | |
Triglycerides: ≥ 150 mg/dL or onTreatment | Triglycerides: ≥ 150 mg/dL or on treatment | Triglycerides: ≥ 150 mg/dL or on treatment | Triglycerides: ≥ 150 mg/dL or on treatment | |
HDL-C: < 35 mg/dL for men and < 39 mg/dL for women | HDL-C: < 40 mg/dL for men and < 50 mg/dL for women | HDL-C: < 40 mg/dL for men and < 50 mg/dL for women | HDL-C: < 40 mg/dL for men and < 50 mg/dL for women or on treatment | |
Urine albumin excretion rate: ≥ 2 0 μg/min or urine albumin to creatinine ratio: ≥3 0 mg/g | WC: ≥ 102 cm for men and ≥ 88 cm for women | WC: ≥ 90 cm for men and ≥ 80 cm for women |
Table 2 Metabolic monitoring guidelines as proposed by various organizations
US consensus[32] | BAP guidelines[86] | |
Weight | At 4 wk, 8 wk, and 12 wk after initiating or changing SGA therapy, then quarterly | BMI weekly for the first 4–6 wk, then every 2–4 wk for up to 12 wk. At a minimum, once every 4 wk for the first 12 wk, then at 6 mo and at least annually |
Blood glucose | Assessed fasting plasma glucose at 3 mo, then annually | Assessed fasting or random plasma glucose in the initial weeks and glycated hemoglobin at 12 wk, 6 mo, and then annually |
Lipid profile | At 3 mo, then repeated at 5-yr intervals if normal | At 12 wk, 6 mo, and then annually. The total cholesterol/high-density lipoprotein cholesterol ratio should be required. |
Blood pressure | At 3 mo, then annually | At 12 wk, 6 mo, and then annually |
- Citation: Chang SC, Goh KK, Lu ML. Metabolic disturbances associated with antipsychotic drug treatment in patients with schizophrenia: State-of-the-art and future perspectives. World J Psychiatr 2021; 11(10): 696-710
- URL: https://www.wjgnet.com/2220-3206/full/v11/i10/696.htm
- DOI: https://dx.doi.org/10.5498/wjp.v11.i10.696