Association and functional study of ATP6V1D and GPHN gene polymorphisms with depression in Chinese population

Figure 1 Schematic diagram of rs3759755, rs10144417, rs2031564, rs8020095 and rs8016024 loci, GPHN gene and ATP6V1D gene location. The two arrows in the figure represent transcription start sites for each of the two genes.

Figure 2 Linkage disequilibrium analysis of five single nucleotide polymorphisms loci.

Figure 3 Effect of polymorphisms on rs8020095 and rs3759755 promoter activity. A: The transcriptional activities of different haplotypes in the rs8020095 promoter region; B: Transcriptional activity of rs3759755 promoter with different haplotypes. ^aP < 0.05; ^bP < 0.01. Data are presented as mean ± SD.