Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression

Figure 1 Traditional Chinese medicine symptom score. ^aP < 0.05 and ^bP < 0.01 vs before treatment; ^cP < 0.05 vs control group.

Figure 2 Cardiac function. A: Left ventricular ejection fraction in both groups increased significantly after treatment; B: Left ventricular end-diastolic diameter in both groups decreased significantly after treatment; C: Both groups showed significantly reduced Left ventricular end-systolic diameter after treatment. ^aP < 0.05 and ^bP < 0.01 vs before treatment; ^cP < 0.05 vs control group. LVEF: Left ventricular ejection fraction; LVEDD: Left ventricular end-diastolic diameter; LVESD: Left ventricular end-systolic diameter.

Figure 3 Negative emotions. A: Both groups had significantly reduced Self-Rating Depression Scale scores after treatment; B: Both groups had significantly reduced Hamilton Depression Scale scores after treatment. ^aP < 0.05 and ^bP < 0.01 vs before treatment; ^cP < 0.05 vs control group. HAMD: Hamilton Depression Scale; SDS: Self-Rating Depression Scale.

Figure 4 Serum inflammatory factors. A: Levels of high-sensitivity C-reactive protein in both groups decreased significantly after treatment; B: Levels of monocyte chemoattractant protein-1 in both groups decreased significantly after treatment; C: Levels of matrix metalloproteinase-9 in both groups decreased significantly after treatment. ^aP < 0.05 and ^bP < 0.01 vs before treatment; ^cP < 0.05 vs control group. hs-CRP: High-sensitivity C-reactive protein; MCP-1: Monocyte chemoattractant protein-1; MMP-9: Matrix metalloproteinase-9.