Research progress on the mechanism of exercise against depression

doi:10.5498/wjp.v14.i11.1611

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Nov 19, 2024 (publication date) through Dec 23, 2024

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Nov 19, 2024; 14(11): 1611-1617
Published online Nov 19, 2024. doi: 10.5498/wjp.v14.i11.1611

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Figure 1 Exercise improves depression by modulating neurotransmitters, neuroplasticity, the immune system, and hormonal pathways. DA: Dopamine; BDNF: Brain-derived neurotrophic factor; CORT: Cortisol; 5-HT: 5-hydroxy tryptamine; NE: Norepinephrine.

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Figure 2 Molecular mechanisms underlying exercise's antidepressant effects. DA: Dopamine; BDNF: Brain-derived neurotrophic factor; CORT: Cortisol; 5-HT: 5-hydroxy tryptamine; NE: Norepinephrine; HPA: Hypothalamic-pituitary-adrenal; PLC: phospholipase C; PGC-1α: Proliferator-activated receptor-gamma coactivator 1-alpha.

Citation: Zhao YL, Sun SY, Qin HC, Zhu YL, Luo ZW, Qian Y, Chen S. Research progress on the mechanism of exercise against depression. World J Psychiatry 2024; 14(11): 1611-1617
URL: https://www.wjgnet.com/2220-3206/full/v14/i11/1611.htm
DOI: https://dx.doi.org/10.5498/wjp.v14.i11.1611