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Copyright ©The Author(s) 2021.
World J Psychiatr. Nov 19, 2021; 11(11): 1065-1074
Published online Nov 19, 2021. doi: 10.5498/wjp.v11.i11.1065
Figure 1
Figure 1 Interleukin-33/suppressor of tumorigenicity 2 axis as a crossroad in schizophrenia-breast cancer comorbidity. Higher serum levels of interleukin-33 (IL-33) have been measured in a psychotic episode of schizophrenia, and IL-33 is also significantly higher in serum and portends tumor recurrence in patients with breast cancer. IL-33: Interleukin-33.
Figure 2
Figure 2 Estrogen receptor modulators and antipsychotics in interleukin-33 targeting strategies. A: Raloxifene could be tissue-specific and improve cognition. B: Tamoxifen resistance in breast carcinoma could be improved by antipsychotics targeting IL-33. IL-33: Interleukin-33.