She has, mainly,  considered the multi-disciplinary strategy  in Cancer Genetics and tumor biology through  her academic and research life through 34 years  at Tehran University. She tried to puzzle the road maps in different neoplasms by considering the follow-up manner through the patients' pedigrees.Meanwhile my collaborations  and  scientific links  with DKFZ, Institutes of Human Genetics and Institute of Medical Genetics in Erlangen-Nuerenberg, Bonn, Humboldt/berlin, Dresden- and Manchester- University, was the remarkable period. Regarding her PhD, she has  initiated a Cancer Genetic project on leukemia at Department of Genetics, Royal Liverpool hospital, University of Liverpool. She has also explored  different tumors to unmask hypotheses and cancer biomarker. She has  established an early single-cell based detection,  through circulating tumor cells (CTCS) in different neoplasms. Unmasking the metastatic model from brain tumor to the host destination was another destination of her research projects. The personalized  cancer managements and offering the  specific  targets for  therapeutic innovation were also my tasks during last 20 years.