Basic Study
Copyright ©The Author(s) 2025.
World J Exp Med. Jun 20, 2025; 15(2): 102897
Published online Jun 20, 2025. doi: 10.5493/wjem.v15.i2.102897
Table 1 Body weight of nude mice treated with GO-Y030, mean ± SD
Body weight (g)
Day 1
Day 3
Day 6
P value
Control21.98 ± 1.3024.98 ± 1.1024.24 ± 1.220.55
GO-Y030 (1 mg/kg, ip)23.7 ± 1.9724.92 ± 0.9224.2 ± 0.84
GO-Y030 (2 mg/kg, ip)22.04 ± 1.5225.02 ± 1.2424.42 ± 1.18
Table 2 In vivo distribution of GO-Y030
Times after administration (hour)
1
3
6
Blood concentration (ng/mL)18.046.758.2
Brain distribution (pg/mg tissue)026.823.1