Opinion Review
Copyright ©The Author(s) 2024.
World J Exp Med. Mar 20, 2024; 14(1): 89320
Published online Mar 20, 2024. doi: 10.5493/wjem.v14.i1.89320
Figure 1
Figure 1 Insulin synthesis and secretion by the pancreatic beta-cell.
Figure 2
Figure 2 The molecule of proinsulin with its components.
Figure 3
Figure 3 The different stages of prevention in treating gestational diabetes and the development of insulin resistance during pregnancy. Primary prevention can only be sought before conception. Secondary prevention is feasible during the period from conception to around the 20th week of gestation, after which prevention of hyperglycemia is not possible and only complications can be potentially avoided; There is a substantial increase in insulin resistance from gestational week 15 until week 35. Then, it remains stable (or slightly decreases) until delivery and returns to the pre-pregnancy state a few days after parturition.