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Copyright ©The Author(s) 2015.
World J Exp Med. Nov 20, 2015; 5(4): 225-231
Published online Nov 20, 2015. doi: 10.5493/wjem.v5.i4.225
Table 1 Relation of P-glycoprotein with disease modifying antirheumatic drugs and immunosuppressants
DrugPharmacological substrates of P-glycoproteinCompetitive inhibitor of P-glycoprotein
CorticosteroidsYesNo
CyclosporineYesYes
TacrolimusYesYes
MethotrexateNoNo
LeflunomideNoNo
HydroxycloroquineYesYes
SulfasalazineYesUnknown
D-penicillamineYesUnknown
ColchicineYesNo
CyclophosphamideNoNo
AzathioprineNoNo