Incidence and outcome of rhabdomyolysis after type A aortic dissection surgery: A retrospective analysis

Table 1 Preoperative and intraoperative characteristics

Parameter	Group non-RML, n = 12	Group RML, n = 21	P value
Age	46.75 ± 14.23	44.38 ± 11.87	0.56
Sex: Female	2 (16.7)	1 (4.8)	0.25
Body mass index	26.14 ± 3.33	32.08 ± 14.92	0.07
Delay from the onset of symptoms to hospital admission	52.81 ± 104.53	26.85 ± 33.67	0.03
Preoperative Hb in gm/dL	12.95 ± 1.86	13.41 ± 1.80	0.97
Preoperative liver function (alanine aminotransferase) unit/liter	47.33 ± 36.97	52.47 ± 39.77	0.76
Preoperative ejection fraction	48.80 ± 9.48	49.62 ± 7.07	0.81
Preoperative cardiac arrest	0 (0)	1 (4.8)	0.44
Preop renal artery involvement by dissection	3 (25)	9 (43)	0.30
Preop peripheral/visceral malperfusion	1 (8.3)	6 (28.5)	0.39
Preoperative mechanical ventilation	0 (0)	1 (4.8)	0.44
Euroscore-logistic	20.22 ± 14.83	16.27 ± 13.30	0.52
Additive euroscore	11.5 ± 3.46	11.05 ± 2.67	0.75
Anesthesia time in minutes	423.83 ± 73.34	495.57 ± 128.35	0.07
Duration of surgery in minutes	365.83 ± 70.13	433.6 ± 113.00	0.15
Cardiopulmonary bypass time in minutes	200.67 ± 66.11	213.43 ± 63.08	0.73
Femoral Artery cannulation	8 (73)	13 (62)	0.823

Data are n (%) or mean ± SD. RML: Rhabdomyolysis.

Table 2 Outcome variables

Parameter	Group non-RML	Group RML	P value
Peak creatinine in mmol/L	113.25 ± 44.79	250.01 ± 165.50	< 0.01
Change in creatinine in mmol/L	18.75 ± 30.04	124.33 ± 129.48	< 0.01
Peak troponin in ng/mL	1243.23 ± 794.63	6257. 48 ± 9157.77	< 0.01
New acute kidney injury	3 (25)	19 (90)	< 0.01
Mortality	0 (0)	2 (9.5)	0.27
Length of intensive care unit stay in hours	92.83 ± 84.62	120.57 ± 124.73	0.45
Length of hospital stay in days	11.67 ± 6.38	16.52 ± 21.96	0.35
Duration of mechanical ventilation	21.42 ± 25.52	36.68 ± 40.81	0.12
Inotrope duration	22.33 ± 24.86	37.04 ± 47.68	0.25
New post-operative dialysis	0 (0)	4 (19.04)	0.04

Data are n (%) or mean ± SD. RML: Rhabdomyolysis.