Recovery after acute kidney injury requiring kidney replacement therapy in patients with left ventricular assist device: A meta-analysis

Table 1 Study characteristics and outcomes included in the systematic review

Study	Year	Country	Patients	AKI definition	No of patients with AKI	Rate of kidney recovery
Kaltenmaier et al[31]	2000	Germany	LVAD-implantation during 1988-1995; Pulsatile Berlin Heart System HeartMate 2000, Novacor.	KRT	55	3/55 = 6%; Kidney recovery at hospital discharge
Demirozu et al[21]	2011	United States	LVAD implantation during 2003-2009; Continuous HeartMate II	KRT	15	10/15 = 67%; Kidney recovery at 7 mo
Hasin et al[8]	2012	United States	LVAD from 2007 to 2010; Continuous HeartMate II	KRT	8	2/8 = 25%; Kidney recovery at 6 mo
Popov et al[22]	2012	United Kingdom	Patient with end-stage heart failure underwent LVAD implantation-2007-2011; Continuous Heart Ware	KRT	12	10/12 = 83%; Kidney recovery post-op/
Borgi et al[7]	2013	United States	End-stage heart failure LVAD during 2006-2011; Continuous HeartMate II; Heart Ware	AKI (KDIGO); KRT	28; 9	17/28 = 60%; Kidney recovery one month; 4/9 = 44.5%; Kidney recovery after KRT--one month
Sumida et al[23]	2014	Japan	LVAD implantation during 2011-2013; LVAD type not specified	AKI; KDIGO; KRT	11; 6	11/11 = 100%; Kidney recovery at Hospital discharge; 4/6 = 66.6%; Kidney recovery after KRT at hospital discharge
Deschika et al[24]	2016	Germany	LVAD recipients with pre-operative biventricular impairment who received an additionally RVAD	KRT	9	9/9 = 100%; Kidney recovery at hospital discharge
Shebab et al[25]	2016	Australia	Dilated cardiomyopathy and severe biventricular failure -underwent dual HVAD implantation as a bridge to transplant during 2011-2014; Continuous Heart Ware	KRT	4	3/4 = 75%; Kidney recovery at post-op
Nadziakiewicz et al[26]	2016	Portland	Patients with end-stage heart failure underwent LVAD implantation during 2007-2014; Continuous Heart ware, HeartMate II	KRT	7	5/7 = 72%; Kidney recovery after KRT- 2 weeks
Raichlin et al[27]	2016	United States	End-stage heart failure with preexisting kidney dysfunction underwent LVAD implantation -2009-2014; Continuous HeartMate II	KRT	15	6/15 = 40%; Kidney recovery after KRT -one month
Muslem et al[32]	2018	Netherlands, United States	LVAD implantation during 2004-2015; Continuous Heart ware, HeartMate II	KRT	23	14/23 = 61%; Kidney recovery after KRT at one year
Schmack et al[28]	2018	Germany	End-stage heart failure patients underwent LVAD from 2010 to 2017; Continuous Heart Ware	KRT	32	5/32 = 16%; Kidney recovery one-month post-KRT
Shebab et al[29]	2018	Australia	LVAD implantation as a bridge to transplant from 2007 to 2016; Continuous Heart Ware	KRT	19	15/19 = 79%; Kidney recovery after KRT Post-op
Asleh et al[30]	2019	United States	LVAD implantation during 2007-2017; ContinuousHeartMate II; HeartMate III; Heart Ware	KRT	54	18/54 = 33%; Kidney recovery at hospital discharge

AKI: Acute kidney injury; KDIGO: Kidney Disease Improving Global Outcomes; N/A: Not available; KRT: Kidney replacement therapy; LVAD: Left ventricular assist device.